Cyclopropyl methyl bromide, also known as Bromomethylcyclopropane (CAS Number 7051-34-5), is a clear to pale yellow liquid halogenated compound featuring a strained cyclopropane ring and a bromomethyl substituent. With a molecular weight of 135.00 g/mol and molecular formula C4H7Br, this compound acts as a highly reactive alkylating agent. It is predominantly employed in the synthesis of active pharmaceutical ingredients (APIs), fine chemicals, and agrochemical intermediates. The presence of the bromine atom endows the molecule with excellent reactivity, facilitating selective substitution reactions critical for constructing complex molecular architectures. Cyclopropyl methyl bromide is prized in medicinal chemistry applications for its capacity to enhance biological activity, metabolic stability, and receptor binding affinity via cyclopropyl group incorporation. Its volatility and flammability require storage under cool, ventilated, and light-protected conditions with appropriate safety measures in place. Packaged in 25 kg drums, it dissolves readily in organic solvents, making it an accessible reagent for industrial chemical manufacturing and pharmaceutical research.
Key Features
| Features | Description |
|---|---|
| Chemical Identity | Cyclopropyl methyl bromide / Bromomethylcyclopropane |
| CAS Number | 7051-34-5 |
| Molecular Formula | C4H7Br |
| Molecular Weight | 135.00 g/mol |
| Appearance | Clear to pale yellow liquid |
| Reactivity | Highly reactive bromomethyl group enabling selective alkylation |
| Primary Use | Alkylating agent in API, fine chemicals, agrochemical synthesis |
| Solubility | Soluble in organic solvents |
| Packaging | 25 kg drum |
| Storage Requirements | Cool, ventilated area away from light |
| Safety Considerations | Volatile, flammable, harmful if inhaled |
| Attributes | Description |
|---|---|
| Chemical Structure | Strained three-membered cyclopropane ring with bromomethyl substituent |
| Physical State | Liquid |
| Color | Clear to pale yellow |
| Volatility | High |
| Flammability | High |
| Toxicity | Harmful by inhalation |
| Storage Conditions | Store in cool, ventilated, and dark environment |
| Application Fields | Pharmaceuticals, agrochemicals, fine chemicals synthesis |
| Packaging Size | 25 kilograms per drum |
| Solvent Compatibility | Soluble in organic solvents such as ethers, esters, hydrocarbons |
*Disclaimer: The above description has been AI-generated and has not been audited or verified for accuracy. It is recommended to verify product details independently before making any purchasing decisions.
Its bromomethyl substituent provides high reactivity allowing selective nucleophilic substitution reactions, while the cyclopropyl ring enhances molecular properties relevant to medicinal chemistry, like metabolic stability and biological activity.
It should be stored in a cool, well-ventilated, and dark area to minimize volatility and degradation, while preventing fire hazards due to its flammability.
It serves as a key building block intermediate for synthesizing agrochemical compounds requiring cyclopropyl functionalization, improving potency and environmental stability.
Handling should occur under controlled ventilation with appropriate personal protective equipment to avoid inhalation exposure and to manage its flammability risk.
No, cyclopropyl methyl bromide is soluble in organic solvents but not in water, so it is typically used in organic solvent media for most synthetic processes.
Country Of Origin: India
Cyclopropyl methyl bromide is a reactive halogenated compound characterized by the presence of a strained three-membered cyclopropane ring and a bromomethyl substituent. This clear to pale yellow liquid is widely used as an alkylating agent in the synthesis of active pharmaceutical ingredients (APIs), fine chemicals, and intermediates. The bromine atom imparts high reactivity, allowing for selective substitution reactions in a variety of synthetic applications. Cyclopropyl groups are increasingly valued in medicinal chemistry for their ability to modify biological activity, metabolic stability, and binding affinity. Due to its volatility and flammability, it must be handled under controlled, ventilated conditions.
Description: Cyclopropyl methyl bromide is a reactive halogenated compound characterized by the presence of a strained three-membered cyclopropane ring and a bromomethyl substituent. This clear to pale yellow liquid is widely used as an alkylating agent in the synthesis of active pharmaceutical ingredients (APIs), fine chemicals, and intermediates. The bromine atom imparts high reactivity, allowing for selective substitution reactions in a variety of synthetic applications. Cyclopropyl groups are increasingly valued in medicinal chemistry for their ability to modify biological activity, metabolic stability, and binding affinity. Due to its volatility and flammability, it must be handled under controlled, ventilated conditions.
Product Summary: CAS Number: 7051-34-5
Molecular Formula: C4H7Br
Molecular Weight: 135.00 g/mol
Synonyms: Bromomethylcyclopropane
Packaging: 25 kg drum
Solubility: Soluble in organic solvents
Storage: Cool, ventilated area, away from light
Toxicity: Flammable, harmful by inhalation
Applications:
Intermediate in API synthesis
Agrochemical building block
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