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Ethyl-2-Chloro acetoacetate

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Ethyl-2-Chloro acetoacetate is a highly reactive ester compound widely utilized as a key intermediate in the synthesis of various pharmaceuticals, agrochemicals, and dyes. Featuring both a chloroacetyl group and an ester functional group, this compound exhibits excellent reactivity in enolate chemistry and nucleophilic substitution reactions. Its specific structural attributes facilitate efficient synthesis pathways in the production of barbiturates, antimalarial drugs, and heterocyclic compounds. Renowned for its good solubility in alcohols and ethers, and its ability to react under mild conditions, Ethyl-2-Chloro acetoacetate is a fundamental reagent for chemical manufacturers aiming to produce high-quality specialty chemicals and active pharmaceutical ingredients (APIs). Packaged securely in 200 kg HDPE drums, it ensures bulk supply stability while maintaining chemical integrity. The compound must be stored in sealed, light-protected containers to preserve its stability and performance. Due to its irritant nature to skin and eyes, appropriate safety measures are essential when handling, underscoring its industrial use in controlled manufacturing environments.

Key Features

Features Description
Chemical Structure Contains chloroacetyl group and ester functionality
Reactivity Highly reactive in enolate chemistry and nucleophilic substitution
Applications Used in synthesis of pharmaceuticals, agrochemicals, and dyes
Solubility Soluble in alcohols and ethers
Packaging Available in 200 kg HDPE drums
Storage Requirements Store in sealed containers away from light
Toxicity Irritant to skin and eyes; requires careful handling
Molecular Formula C6H9ClO3
Molecular Weight 164.59 g/mol
CAS Number 609-15-4
Attributes Description
Chemical Name Ethyl-2-Chloro acetoacetate
CAS Number 609-15-4
Molecular Formula C6H9ClO3
Molecular Weight 164.59 g/mol
Appearance Colorless to pale yellow liquid
Purity Typically >98%
Solubility Soluble in alcohols and ethers
Packaging 200 kg HDPE drum
Storage Conditions Sealed container, away from light
Hazards Irritating to skin and eyes; handle with protective equipment

*Disclaimer: The above description has been AI-generated and has not been audited or verified for accuracy. It is recommended to verify product details independently before making any purchasing decisions.

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Ethyl-2-Chloro acetoacetate is primarily utilized in enolate chemistry and nucleophilic substitution reactions, which are key for synthesizing barbiturates, antimalarials, and heterocyclic compounds used in pharmaceuticals.

Yes, it acts as a reactive intermediate facilitating the formation of precursors needed for dye and flavor synthesis, enhancing colorant and flavorant development.

It should be stored in sealed, light-protected containers to prevent degradation and maintain reactivity, typically supplied in 200 kg HDPE drums.

Due to its irritant nature to skin and eyes, appropriate personal protective equipment like gloves and goggles are mandatory during handling.

It is readily soluble in alcohols and ethers, facilitating easy use in various organic synthesis processes under mild conditions.

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Country Of Origin: India

Description:
Ethyl-2-chloroacetoacetate is a versatile ester compound used in the preparation of pharmaceuticals, agrochemicals, and dyes. The presence of a chloroacetyl group and an ester functionality makes it a reactive intermediate for enolate chemistry and nucleophilic substitution. It is used in the synthesis of barbiturates, antimalarials, and in heterocyclic chemistry. Its good solubility and reactivity under mild conditions make it an essential synthetic reagent.

Ethyl-2-Chloro acetoacetate

Description:
Ethyl-2-chloroacetoacetate is a versatile ester compound used in the preparation of pharmaceuticals, agrochemicals, and dyes. The presence of a chloroacetyl group and an ester functionality makes it a reactive intermediate for enolate chemistry and nucleophilic substitution. It is used in the synthesis of barbiturates, antimalarials, and in heterocyclic chemistry. Its good solubility and reactivity under mild conditions make it an essential synthetic reagent.

Product Summary:

  • CAS Number: 609-15-4

  • Molecular Formula: C6H9ClO3

  • Molecular Weight: 164.59 g/mol

  • Synonyms: Ethyl chloroacetoacetate

  • Packaging: 200 kg HDPE drum

  • Solubility: Soluble in alcohols, ethers

  • Storage: Store in sealed containers, away from light

  • Toxicity: Irritating to skin and eyes

Applications:

  • Pharmaceutical intermediate

  • Synthesis of dyes and flavors

  • Agrochemical precursor

 



Ester And Derivatives

Ethyl-2-Chloro Acetoacetate

Ethyl Chloroacetoacetate

Pharmaceutical Intermediate

Agrochemical Precursor

Barbiturate Synthesis

Heterocyclic Chemistry Reagent

Reactive Ester

Nucleophilic Substitution Intermediate

Ethyl-2-Chloro acetoacetate

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avd pharmaceuticals private limited

Pimpri-Chinchwad , India

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