Ethyl-2-Chloro acetoacetate is a highly reactive ester compound widely utilized as a key intermediate in the synthesis of various pharmaceuticals, agrochemicals, and dyes. Featuring both a chloroacetyl group and an ester functional group, this compound exhibits excellent reactivity in enolate chemistry and nucleophilic substitution reactions. Its specific structural attributes facilitate efficient synthesis pathways in the production of barbiturates, antimalarial drugs, and heterocyclic compounds. Renowned for its good solubility in alcohols and ethers, and its ability to react under mild conditions, Ethyl-2-Chloro acetoacetate is a fundamental reagent for chemical manufacturers aiming to produce high-quality specialty chemicals and active pharmaceutical ingredients (APIs). Packaged securely in 200 kg HDPE drums, it ensures bulk supply stability while maintaining chemical integrity. The compound must be stored in sealed, light-protected containers to preserve its stability and performance. Due to its irritant nature to skin and eyes, appropriate safety measures are essential when handling, underscoring its industrial use in controlled manufacturing environments.
Key Features
| Features | Description |
|---|---|
| Chemical Structure | Contains chloroacetyl group and ester functionality |
| Reactivity | Highly reactive in enolate chemistry and nucleophilic substitution |
| Applications | Used in synthesis of pharmaceuticals, agrochemicals, and dyes |
| Solubility | Soluble in alcohols and ethers |
| Packaging | Available in 200 kg HDPE drums |
| Storage Requirements | Store in sealed containers away from light |
| Toxicity | Irritant to skin and eyes; requires careful handling |
| Molecular Formula | C6H9ClO3 |
| Molecular Weight | 164.59 g/mol |
| CAS Number | 609-15-4 |
| Attributes | Description |
|---|---|
| Chemical Name | Ethyl-2-Chloro acetoacetate |
| CAS Number | 609-15-4 |
| Molecular Formula | C6H9ClO3 |
| Molecular Weight | 164.59 g/mol |
| Appearance | Colorless to pale yellow liquid |
| Purity | Typically >98% |
| Solubility | Soluble in alcohols and ethers |
| Packaging | 200 kg HDPE drum |
| Storage Conditions | Sealed container, away from light |
| Hazards | Irritating to skin and eyes; handle with protective equipment |
*Disclaimer: The above description has been AI-generated and has not been audited or verified for accuracy. It is recommended to verify product details independently before making any purchasing decisions.
Ethyl-2-Chloro acetoacetate is primarily utilized in enolate chemistry and nucleophilic substitution reactions, which are key for synthesizing barbiturates, antimalarials, and heterocyclic compounds used in pharmaceuticals.
Yes, it acts as a reactive intermediate facilitating the formation of precursors needed for dye and flavor synthesis, enhancing colorant and flavorant development.
It should be stored in sealed, light-protected containers to prevent degradation and maintain reactivity, typically supplied in 200 kg HDPE drums.
Due to its irritant nature to skin and eyes, appropriate personal protective equipment like gloves and goggles are mandatory during handling.
It is readily soluble in alcohols and ethers, facilitating easy use in various organic synthesis processes under mild conditions.
Country Of Origin: India
Description:
Ethyl-2-chloroacetoacetate is a versatile ester compound used in the preparation of pharmaceuticals, agrochemicals, and dyes. The presence of a chloroacetyl group and an ester functionality makes it a reactive intermediate for enolate chemistry and nucleophilic substitution. It is used in the synthesis of barbiturates, antimalarials, and in heterocyclic chemistry. Its good solubility and reactivity under mild conditions make it an essential synthetic reagent.
Description:
Ethyl-2-chloroacetoacetate is a versatile ester compound used in the preparation of pharmaceuticals, agrochemicals, and dyes. The presence of a chloroacetyl group and an ester functionality makes it a reactive intermediate for enolate chemistry and nucleophilic substitution. It is used in the synthesis of barbiturates, antimalarials, and in heterocyclic chemistry. Its good solubility and reactivity under mild conditions make it an essential synthetic reagent.
Product Summary:
CAS Number: 609-15-4
Molecular Formula: C6H9ClO3
Molecular Weight: 164.59 g/mol
Synonyms: Ethyl chloroacetoacetate
Packaging: 200 kg HDPE drum
Solubility: Soluble in alcohols, ethers
Storage: Store in sealed containers, away from light
Toxicity: Irritating to skin and eyes
Applications:
Pharmaceutical intermediate
Synthesis of dyes and flavors
Agrochemical precursor
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