Benfotiamine is a highly bioavailable fat-soluble derivative of thiamine (vitamin B1) designed for therapeutic and nutraceutical applications. This Active Pharmaceutical Ingredient (API) with CAS Number 22457-89-2 is widely used in the development of supplements and formulations aimed at supporting diabetic neuropathy, cardiovascular health, and improving metabolic function. Benfotiamine’s unique lipid-soluble nature allows for superior absorption and retention in body tissues compared to thiamine hydrochloride, making it particularly effective in clinical and commercial nutraceutical products. Its potent antioxidant properties help combat oxidative stress and advanced glycation end products (AGEs), which are implicated in diabetes complications and other metabolic disorders. Ideal for use in pharmaceutical-grade, dietary supplements, and functional food manufacturing, this high-purity benfotiamine API supports formulations targeting nerve protection, glucose metabolism, and general wellness enhancement in diabetic and at-risk populations.
Key Features
| Features | Description |
|---|---|
| CAS Number | 22457-89-2 |
| Chemical Nature | Fat-soluble derivative of Vitamin B1 (thiamine) |
| Bioavailability | Higher tissue absorption compared to regular thiamine |
| Applications | Pharmaceuticals, nutraceuticals, dietary supplements |
| Therapeutic Benefits | Supports diabetic neuropathy, cardiovascular health, and oxidative stress reduction |
| Formulation Type | Active Pharmaceutical Ingredient (API) |
| Purity Level | Pharmaceutical grade |
| Stability | Stable in lipid-based formulations |
| Attributes | Description |
|---|---|
| Molecular Formula | C19H23N4O6PS |
| Molecular Weight | 466.46 g/mol |
| Appearance | White to off-white crystalline powder |
| Solubility | Soluble in organic solvents, lipid soluble |
| Melting Point | 120-123°C |
| Purity | ≥ 98% (HPLC) |
| Storage Conditions | Store in a cool, dry place away from light |
| Shelf Life | 2 years under recommended storage |
*Disclaimer: The above description has been AI-generated and has not been audited or verified for accuracy. It is recommended to verify product details independently before making any purchasing decisions.
Benfotiamine is fat-soluble, allowing better absorption and higher bioavailability in tissues than water-soluble thiamine hydrochloride, making it more effective for neurologic and metabolic therapeutic applications.
Yes, due to its efficacy in improving glucose metabolism and reducing oxidative stress, this pharmaceutical-grade Benfotiamine API is ideal for formulating diabetic neuropathy and cardiovascular health supplements.
The Benfotiamine offered has a purity of 98% or higher as verified by HPLC analysis, ensuring pharmaceutical-grade quality.
Benfotiamine is stable when stored in cool, dry conditions away from light and performs well in lipid-based formulations without significant degradation over its two-year shelf life.
Yes, its high purity and bioavailability make it suitable for a broad range of formulations in both pharmaceutical drugs and nutritional supplements.
Brand: altezza life
Country Of Origin: India
Benfotiamine API
CAS Number: 22457-89-2
HSN Code: 2936 29 90
Description:
Benfotiamine is a lipid-soluble derivative of thiamine (vitamin B1) that offers superior bioavailability compared to conventional thiamine salts. It is widely used in the formulation of nutraceutical and pharmaceutical preparations for the prevention and treatment of diabetic complications, neuropathies, and oxidative stress-related disorders.
Therapeutic Category:
Vitamin / Antineuropathic / Antioxidant
Mechanism of Action:
Benfotiamine enhances the activity of transketolase, an enzyme critical to glucose metabolism, thereby reducing the formation of advanced glycation end-products (AGEs). This mechanism helps in preventing nerve and vascular damage associated with diabetes and oxidative stress.
Applications:
Technical Specifications:
Appearance: White or off-white crystalline powder
Solubility: Soluble in methanol and ethanol; practically insoluble in water
Assay (on dried basis): ≥ 98.0%
Molecular Formula: C₁₉H₂₃N₄O₆PS
Molecular Weight: 466.45 g/mol
Available Grades:
Pharma Grade (IH)
Packaging:
Available in 1 kg, 5 kg, and 25 kg HDPE or fiber drums with inner double polyethylene liners.
Storage:
Store in a well-closed container, protected from moisture and light, below 25°C.
