Clozapine is a highly potent atypical antipsychotic specifically synthesized for the management of treatment-resistant schizophrenia and reduction of suicidal behavior in schizophrenic patients. Unlike conventional antipsychotics, Clozapine exhibits superior efficacy due to its unique pharmacological profile as an antagonist of dopamine D₄ and serotonin 5-HT₂A receptors, addressing both positive and negative symptoms effectively. Supplied as a high-purity yellow crystalline powder with an assay of ≥ 98.0%, this product is available in multiple pharmacopeial grades including IP, BP, and USPP, catering to various regulatory requirements in pharmaceutical manufacturing. Packaged conveniently in 1 kg, 5 kg, and 25 kg HDPE drums, Clozapine ensures secure transportation and storage stability. Ideal for pharmaceutical companies and contract manufacturers producing antipsychotic formulations, this product demands storage in cool, dry, and light-protected environments to maintain its pharmaceutical grade efficacy.
Key Features
| Features | Description |
|---|---|
| Chemical Name | Clozapine |
| APICAS Number | 5786-21-0 |
| HSN Code | 2933 99 00 |
| Appearance | Yellow crystalline powder |
| Assay Purity | ≥ 98.0% |
| Molecular Formula | C18H19ClN4 |
| Molecular Weight | 326.82 g/mol |
| Pharmacopoeial Grades Available | IP / BP / USPP |
| Packaging Options | 1 kg, 5 kg, 25 kg HDPE drums |
| Storage Condition | Cool, dry place, protected from light |
| Therapeutic Category | Antipsychotic / CNS Agent |
| Primary Indication | Treatment-resistant schizophrenia |
| Additional Application | Reduction of suicidal behavior in schizophrenic patients |
| Attributes | Description |
|---|---|
| Chemical Structure | Clozapine is a dibenzodiazepine derivative |
| Mode of Action | Antagonist of dopamine D4 and serotonin 5-HT2A receptors |
| Physical State | Solid |
| Color | Yellow |
| Form | Crystalline powder |
| Solubility | Sparingly soluble in water, soluble in organic solvents |
| Shelf Life | As per standard pharmaceutical guidelines |
| Regulatory Compliance | Provides APIs in IP, BP, and USPP grade compliant forms |
| Packaging Material | High-Density Polyethylene (HDPE) drums |
| Transport Classification | Chemical substance requiring careful handling, non-hazardous under normal conditions |
*Disclaimer: The above description has been AI-generated and has not been audited or verified for accuracy. It is recommended to verify product details independently before making any purchasing decisions.
Clozapine is available in multiple pharmacopeial grades including IP (Indian Pharmacopoeia), BP (British Pharmacopoeia), and USPP (United States Pharmacopeia), ensuring compliance with regional pharmaceutical manufacturing standards.
The Clozapine API is supplied in HDPE drums of 1 kg, 5 kg, and 25 kg capacities, which protect the product from moisture, light exposure, and contamination during storage and transport.
Clozapine selectively antagonizes dopamine D4 and serotonin 5-HT2A receptors, mechanisms not targeted effectively by conventional antipsychotics, which improves both positive and negative symptoms and reduces suicidal behavior in patients.
Clozapine should be stored in a cool, dry place away from direct light to prevent degradation and to maintain its chemical purity and therapeutic efficacy.
Yes, the Clozapine provided meets high purity assay standards (≥ 98.0%) and is available in pharmaceutical grades suitable for direct incorporation into finished dosage forms by pharmaceutical manufacturers.
Country Of Origin: India
Clozapine API
CAS Number: 5786-21-0
HSN Code: 2933 99 00
Description:
Clozapine is an atypical antipsychotic primarily used in the management of treatment-resistant schizophrenia. It offers superior efficacy in patients unresponsive to conventional antipsychotics.
Therapeutic Category:
Antipsychotic / CNS Agent
Mechanism of Action:
Clozapine acts by antagonizing dopamine D₄ and serotonin 5-HT₂A receptors, improving both positive and negative symptoms of schizophrenia.
Applications:
Technical Specifications:
Appearance: Yellow crystalline powder
Assay: ≥ 98.0%
Molecular Formula: C₁₈H₁₉ClN₄
Molecular Weight: 326.82 g/mol
Available Grades: IP / BP / USP
Packaging: 1 kg, 5 kg, 25 kg HDPE drums
Storage: Store in a cool, dry place, protected from light
