Methylprednisolone is a high-purity synthetic glucocorticoid API with potent anti-inflammatory and immunosuppressive efficacy. This pharmaceutical-grade corticosteroid is extensively used in the development of oral tablets, injectables, and topical formulations treating a wide range of allergic, inflammatory, and autoimmune disorders. Its mechanism involves immune response modulation by suppressing pro-inflammatory cytokines and inhibiting leukocyte migration, effectively controlling inflammation and hypersensitivity reactions. Methylprednisolone API is characterized by a white crystalline powder appearance, with high assay purity of ≥ 98.0%, compliant with IP, BP, USP, and EP standards. It is practically insoluble in water but soluble in organic solvents such as acetone, ethanol, and methanol, facilitating versatile formulation compatibility. Supplied in secure HDPE containers or fiber drums, this corticosteroid API requires storage under controlled conditions to maintain stability. Its formulation compatibility, potency, and compliance make it ideal for pharmaceutical manufacturers focusing on corticosteroid drugs for severe allergic disorders, rheumatoid arthritis, lupus, cancer adjunct therapy, transplant rejection, and acute inflammation management.
Key Features
| Features | Description |
|---|---|
| Chemical Name | Methylprednisolone |
| APICAS Number | 83-43-2 |
| HSN Code | 2942 00 90 |
| Therapeutic Category | Corticosteroid / Anti-inflammatory / Immunosuppressant |
| Purity Assay | ≥ 98.0% (dry basis) |
| Physical Form | White or almost white crystalline powder |
| Solubility | Practically insoluble in water; soluble in acetone, ethanol, methanol |
| Compliance Grades | Pharma Grade (IP / BP / USP / EP compliant) |
| Packaging Options | 1 kg, 5 kg, and 25 kg HDPE containers or fiber drums with double polyethylene liners |
| Storage Conditions | Store in a tightly closed container, protected from light and moisture at ≤ 25°C |
| Attributes | Description |
|---|---|
| Molecular Formula | C22H30O5 |
| Molecular Weight | 374.47 g/mol |
| Mechanism of Action | Modulates immune response by inhibiting pro-inflammatory cytokines and leukocyte migration |
| Applications | Severe allergic disorders, asthma, rheumatoid arthritis, lupus, cancer adjunct therapy, transplant rejection |
| Appearance | White crystalline powder |
| Solubility Details | Insoluble in water, soluble in acetone, ethanol, methanol |
| Pharmacopoeia Compliance | IP, BP, USP, EP |
*Disclaimer: The above description has been AI-generated and has not been audited or verified for accuracy. It is recommended to verify product details independently before making any purchasing decisions.
Methylprednisolone API is available in Pharma Grade compliant with major pharmacopoeia including IP, BP, USP, and EP, suitable for oral, injectable, and topical formulation development.
It should be stored in tightly closed containers, protected from light and moisture, at temperatures not exceeding 25°C to preserve its purity and efficacy.
No, Methylprednisolone API is practically insoluble in water but soluble in organic solvents like acetone, ethanol, and methanol, requiring appropriate formulation techniques for injectables.
It is primarily used in formulations for severe allergic disorders, asthma, rheumatoid arthritis, lupus, acute inflammation control, cancer adjunct therapy, and prevention of transplant rejection.
The API is available in 1 kg, 5 kg, and 25 kg HDPE containers or fiber drums with double polyethylene liners ensuring safety during storage and transportation.
Brand: altezza life
Country Of Origin: India
Methylprednisolone API
CAS Number: 83-43-2
HSN Code: 2942 00 90
Description:
Methylprednisolone is a synthetic glucocorticoid used for its potent anti-inflammatory and immunosuppressive properties. It is an important corticosteroid API widely utilized in the formulation of oral, injectable, and topical dosage forms for managing various allergic, inflammatory, and autoimmune conditions.
Therapeutic Category:
Corticosteroid / Anti-inflammatory / Immunosuppressant
Mechanism of Action:
Methylprednisolone acts by modulating the immune response and inhibiting the release of pro-inflammatory cytokines. It reduces inflammation and allergic reactions by suppressing the migration of polymorphonuclear leukocytes and reversing capillary permeability.
Applications:
Technical Specifications:
Appearance: White or almost white crystalline powder
Solubility: Practically insoluble in water; soluble in acetone, ethanol, and methanol
Assay (on dried basis): ≥ 98.0%
Molecular Formula: C₂₂H₃₀O₅
Molecular Weight: 374.47 g/mol
Available Grades:
Pharma Grade (IP / BP / USP / EP compliant)
Packaging:
Available in 1 kg, 5 kg, and 25 kg HDPE containers or fiber drums with double polyethylene liners.
Storage:
Store in a tightly closed container, protected from light and moisture, at a temperature not exceeding 25°C.
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