Ondansetron Hydrochloride is a high-purity, selective serotonin 5-HT₃ receptor antagonist specifically formulated for medical and pharmaceutical applications. It effectively prevents and treats nausea and vomiting caused by chemotherapy, radiation therapy, postoperative recovery, and gastroenteritis. This white to off-white crystalline powder exhibits an assay purity of ≥ 98.0%, ensuring consistent therapeutic efficacy. Ondansetron Hydrochloride works by blocking serotonin receptors in both the chemoreceptor trigger zone within the brain and the gastrointestinal tract, halting the emetic signaling pathways. Available in pharmaceutical-grade IP, BP, and USPP grades, this compound is supplied in secure HDPE drums in bulk sizes of 5 kg and 25 kg, designed to maintain stability during storage and transport. It is ideal for integration into antiemetic drug formulations aimed at clinical use in oncology, surgery, and gastrointestinal care centers.
Key Features
| Features | Description |
|---|---|
| Chemical Name | Ondansetron Hydrochloride |
| APICAS Number | 99614-02-5 |
| HSN Code | 2933 39 90 |
| Therapeutic Category | Antiemetic / Gastrointestinal Agent |
| Mechanism of Action | Selective serotonin 5-HT₃ receptor antagonist blocking receptors in the chemoreceptor trigger zone and gastrointestinal tract |
| Applications | Chemotherapy, radiation, and postoperative induced nausea and vomiting; gastroenteritis-induced nausea |
| Purity Assay | ≥ 98.0% |
| Available Grades | IP / BP / USPP |
| Packaging | 5 kg and 25 kg HDPE drums |
| Storage Instructions | Store in a cool, dry place away from light |
| Attributes | Description |
|---|---|
| Appearance | White to off-white crystalline powder |
| Molecular Formula | C₁₈H₁₉N₃O · HCl |
| Molecular Weight | 365.83 g/mol |
| Assay Purity | ≥ 98.0% |
| Grades Offered | Indian Pharmacopoeia (IP), British Pharmacopoeia (BP), United States Pharmacopeia (USPP) |
| Packaging Type | High-density polyethylene (HDPE) drums |
| Package Sizes | 5 kg, 25 kg |
| Storage Conditions | Cool, dry place; protected from light |
*Disclaimer: The above description has been AI-generated and has not been audited or verified for accuracy. It is recommended to verify product details independently before making any purchasing decisions.
Ondansetron Hydrochloride is available in Indian Pharmacopoeia (IP), British Pharmacopoeia (BP), and United States Pharmacopeia (USPP) pharmaceutical grades to meet diverse regulatory requirements.
It selectively blocks serotonin 5-HT3 receptors in both the chemoreceptor trigger zone and gastrointestinal tract, disrupting the signals that cause nausea and vomiting associated with chemotherapy.
The product is securely packed in 5 kg and 25 kg high-density polyethylene (HDPE) drums designed to protect the crystalline powder from moisture and light exposure.
Yes, Ondansetron Hydrochloride is specifically indicated for preventing and treating nausea and vomiting caused by radiation therapy.
It should be stored in a cool, dry place, away from direct light, to maintain its purity and prevent degradation.
Country Of Origin: India
Ondansetron Hydrochloride API
CAS Number: 99614-02-5
HSN Code: 2933 39 90
Description:
Ondansetron Hydrochloride is a selective serotonin 5-HT₃ receptor antagonist used for the prevention and treatment of nausea and vomiting induced by chemotherapy, radiation, or surgery.
Therapeutic Category:
Antiemetic / Gastrointestinal Agent
Mechanism of Action:
It blocks serotonin receptors in the chemoreceptor trigger zone and gastrointestinal tract, thereby preventing emesis.
Applications:
Technical Specifications:
Appearance: White to off-white crystalline powder
Assay: ≥ 98.0%
Molecular Formula: C₁₈H₁₉N₃O · HCl
Molecular Weight: 365.83 g/mol
Available Grades: IP / BP / USP
Packaging: 5 kg and 25 kg HDPE drums
Storage: Store in a cool, dry place away from light
