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Ketosulfone is a high-purity pharmaceutical intermediate essential for the synthesis of Etoricoxib, a selective COX-2 inhibitor widely used in anti-inflammatory treatments. Exhibiting both ketone and sulfone functional groups, Ketosulfone enables versatile synthetic modifications, notably facilitating cyclization and ring-closing reactions crucial in the formation of Etoricoxib's molecular structure. Manufactured under GMP-like stringent conditions, this intermediate guarantees consistency, safety, and efficacy in the downstream production of the final drug. Its solubility profile in solvents like dichloromethane (DCM) and methanol enhances its process adaptability in pharmaceutical manufacturing environments. With an emphasis on stability by requiring storage in cool, dry places and minimizing moisture exposure, Ketosulfone ensures a reliable raw material supply. This intermediate is critical not only for drug synthesis but also serves as a valuable building block in heterocyclic compound research and development related to COX-2 inhibitor chemistries.
Key Features
| Features | Description |
|---|---|
| Pharmaceutical Application | Intermediate in Etoricoxib synthesis, a selective COX-2 inhibitor |
| Functional Groups | Contains ketone and sulfone groups enabling versatile synthetic transformations |
| Purity Standard | High purity manufactured under GMP-like conditions |
| Chemical Stability | Stable when stored in cool, dry conditions avoiding moisture |
| Solubility | Soluble in dichloromethane (DCM) and methanol |
| Packaging | Available in 25 kg fiber drums for bulk pharmaceutical use |
| Safety Profile | Non-carcinogenic, though prolonged exposure should be avoided |
| Molecular Information | Molecular Weight: 224.23 g/mol; Molecular Formula: C10H8O4S |
| Research Utility | Used as a building block in heterocyclic compound synthesis and COX-2 inhibitor drug research |
| Attributes | Description |
|---|---|
| CAS Number | 140104-75-6 |
| Molecular Formula | C10H8O4S |
| Molecular Weight | 224.23 g/mol |
| Synonyms | Etoricoxib intermediate |
| Packaging | 25 kg fiber drum |
| Solubility | Soluble in DCM, methanol |
| Storage Conditions | Store in a cool, dry place, avoid moisture exposure |
| Toxicity | Non-carcinogenic; avoid prolonged exposure |
| Manufacturing Standard | Produced under GMP-like conditions ensuring pharmaceutical grade quality |
*Disclaimer: The above description has been AI-generated and has not been audited or verified for accuracy. It is recommended to verify product details independently before making any purchasing decisions.
Ketosulfone is produced under GMP-like conditions that meet stringent pharmaceutical industry standards to guarantee purity, consistency, and suitability for Etoricoxib synthesis.
Ketosulfone is soluble in organic solvents such as dichloromethane (DCM) and methanol, facilitating ease of handling and incorporation in synthesis reactions.
Ketosulfone must be stored in a cool, dry place and protected from moisture exposure to maintain its chemical stability and efficacy as a pharmaceutical intermediate.
The presence of both ketone and sulfone groups enables Ketosulfone to undergo versatile chemical transformations, especially cyclization and ring-closing reactions that are vital steps in the Etoricoxib synthesis pathway.
While Ketosulfone is non-carcinogenic, it is advised to avoid prolonged exposure during handling to ensure safety for manufacturing personnel.
Ketosulfone is supplied in 25 kg fiber drums designed to meet the requirements of large-scale pharmaceutical manufacturing facilities.
Country Of Origin: India
Ketosulfone is a key pharmaceutical intermediate used in the synthesis of Etoricoxib, a selective COX-2 inhibitor. This compound contains both a ketone and sulfone functional group, allowing for versatile synthetic transformations, especially in cyclization and ring-closing reactions. It is a high-purity intermediate, manufactured under GMP-like conditions to ensure suitability for final drug production. Its use is critical in ensuring the efficacy and safety profile of Etoricoxib.
Description:
Ketosulfone is a key pharmaceutical intermediate used in the synthesis of Etoricoxib, a selective COX-2 inhibitor. This compound contains both a ketone and sulfone functional group, allowing for versatile synthetic transformations, especially in cyclization and ring-closing reactions. It is a high-purity intermediate, manufactured under GMP-like conditions to ensure suitability for final drug production. Its use is critical in ensuring the efficacy and safety profile of Etoricoxib.
Product Summary:
CAS Number: 140104-75-6
Molecular Formula: C10H8O4S
Molecular Weight: 224.23 g/mol
Synonyms: Etoricoxib intermediate
Packaging: 25 kg fiber drum
Solubility: Soluble in DCM, methanol
Storage: Cool, dry place; avoid exposure to moisture
Toxicity: Non-carcinogenic; avoid prolonged exposure
Applications:
Intermediate for Etoricoxib synthesis
Used in COX-2 inhibitor drug research
Building block for heterocyclic compounds
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Pimpri-Chinchwad , India
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