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The Waters 186009844 XBridge Premier BEH C18 VanGuard FIT 2.1 mm X 100 mm Column is a high-performance reversed-phase liquid chromatography (LC) column engineered for demanding analytical separations. Featuring a robust BEH (bridged ethyl hybrid) particle technology with 2.5 µm spherical particles and a pore size of 130 Å, this premier column ensures exceptional resolution, high efficiency, and reproducibility in UPLC and UHPLC systems. The column is designed with a 2.1 mm inner diameter and 100 mm length, optimized for rapid and precise analysis of complex mixtures. Its hybrid particle substrate supports a broad pH range from 1 to 12, allowing versatile method development and robustness under extreme conditions. Endcapped to minimize silanol activity, it significantly reduces secondary retention effects, enhancing peak shape and compound selectivity. With a maximum operating pressure of 18000 psi (1240 Bar), the column is suitable for high-pressure applications. The Parker-style endfitting and Premier format ensure compatibility with Waters VanGuard FIT systems, facilitating easy installation and reliable performance. Offering a carbon load of 18%, this L1 classified USP column is ideal for pharmaceutical, biotech, environmental, and chemical analysis industries needing dependable, high-throughput reversed-phase separations.
Key Features
| Features | Description |
|---|---|
| Chromatography Chemistry | C18 reversed phase |
| Particle Technology | BEH (bridged ethyl hybrid) |
| Particle Size | 2.5 µm spherical particles |
| Column Dimensions | 2.1 mm inner diameter x 100 mm length |
| Pore Size | 130 Å |
| pH Operating Range | 1 to 12 |
| Maximum Pressure | 18000 psi (1240 Bar) |
| Endcapped | Yes, low silanol activity |
| Surface Area | 185 m²/g |
| Endfitting Type | Parker-style |
| Format | Premier Column compatible with VanGuard FIT |
| Carbon Load | 18% |
| System Compatibility | UPLC, UHPLC |
| USP Classification | L1 |
| Attributes | Description |
|---|---|
| Chemistry | C18 |
| Separation Mode | Reversed Phase |
| Particle Substrate | Hybrid |
| pH Range Min | 1 |
| pH Range Max | 12 |
| Maximum Pressure | 18000 psi (1240 Bar) |
| Endcapped | Yes |
| Silanol Activity | Low |
| Particle Shape | Spherical |
| Particle Size | 2.5 µm |
| Endfitting Type | Parker-style |
| Pore Size | 130 Å |
| Format | Premier Column |
| Surface Area | 185 m²/g |
| System | UPLC, UHPLC |
| Particle Technology | BEH |
| Technique | LC |
| USP Classification | L1 |
| Inner Diameter | 2.1 mm |
| Length | 100 mm |
| Carbon Load | 18% |
| Brand | XBridge |
| Product Type | Columns |
*Disclaimer: The above description has been AI-generated and has not been audited or verified for accuracy. It is recommended to verify product details independently before making any purchasing decisions.
This column is compatible specifically with UPLC and UHPLC systems, and the VanGuard FIT format ensures optimal integration with Waters UPLC systems. Compatibility with other manufacturers’ systems may require adapter fittings.
Yes, with a broad pH operating range of 1 to 12, this hybrid particle column is designed to maintain stability and performance even under aggressive acidic or basic mobile phase conditions.
The column supports a maximum operating pressure of 18000 psi (1240 Bar), making it suitable for high-pressure UPLC or UHPLC applications requiring fast and high-resolution separations.
The column is endcapped to reduce free silanol groups, minimizing secondary interactions, reducing peak tailing, and improving peak shapes especially for basic and polar analytes.
Yes, the 18% carbon load provides a suitable hydrophobic surface for reliable retention of nonpolar compounds while maintaining balanced selectivity for diverse analytes.
Country Of Origin: United States
Specifications
Chemistry
C18
Separation Mode
Reversed Phase
Particle Substrate
Hybrid
pH Range Min
1 pH
pH Range Max
12 pH
Maximum Pressure
18000 psi (1240 Bar)
Endcapped
Yes
Silanol Activity
Low
Particle Shape
Spherical
Particle Size
2.5 µm
Endfitting Type
Parker-style
Pore Size
130 Å
Format
Premier Column
Surface Area
185
System
UPLC, UHPLC
Particle Technology
BEH
Technique
LC
USP Classification
L1
Inner Diameter
2.1 mm
Length
100 mm
Carbon Load
18 %
UNSPSC
41115709
Brand
XBridge
Product Type
Columns
Specifications
Chemistry
C18
Separation Mode
Reversed Phase
Particle Substrate
Hybrid
pH Range Min
1 pH
pH Range Max
12 pH
Maximum Pressure
18000 psi (1240 Bar)
Endcapped
Yes
Silanol Activity
Low
Particle Shape
Spherical
Particle Size
2.5 µm
Endfitting Type
Parker-style
Pore Size
130 Å
Format
Premier Column
Surface Area
185
System
UPLC, UHPLC
Particle Technology
BEH
Technique
LC
USP Classification
L1
Inner Diameter
2.1 mm
Length
100 mm
Carbon Load
18 %
UNSPSC
41115709
Brand
XBridge
Product Type
Columns
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