SYNVISC® Injection is a specialized viscosupplement designed for targeted treatment of knee pain associated with osteoarthritis (OA). Manufactured by Sanofi, this injectable solution harnesses the power of Hylan G-F 20, a high molecular weight hyaluronan derivative, which replicates the natural hyaluronic acid present in healthy synovial fluid. By restoring the viscoelastic properties of the synovial fluid within the knee joint, SYNVISC® Injection effectively improves lubrication and shock absorption, resulting in significant pain relief, reduced stiffness, and enhanced joint mobility. Primarily indicated for patients who have not found adequate relief via conservative treatments such as physiotherapy or oral analgesics, it presents a minimally invasive, non-surgical alternative that can delay or reduce the need for surgical interventions. Administered intra-articularly by trained physicians typically via three weekly injections or a single high-volume dose, SYNVISC® Injection offers long-lasting effects that can persist for up to six months. Packaged in prefilled syringes of 2 mL or 6 mL, this product requires careful storage below 25°C away from light to maintain efficacy. SYNVISC® Injection is a clinically proven and trusted solution for managing the debilitating symptoms of knee osteoarthritis, combining safety with superior functional outcomes.
Key Features
| Features | Description |
|---|---|
| Active Ingredient | Hylan G-F 20 (High molecular weight hyaluronan derivative) |
| Indication | Painful osteoarthritis of the knee |
| Injection Regimen | Typically 3 injections (2 mL each) weekly or a single 6 mL injection (Synvisc-One) |
| Administration Route | Intra-articular injection into the affected knee |
| Mechanism of Action | Restores viscoelasticity of synovial fluid enhancing lubrication and shock absorption |
| Duration of Effect | Up to 6 months in many patients |
| Packaging | Prefilled syringe available in 2 mL or 6 mL |
| Storage Conditions | Store at room temperature below 25°C, protect from light, do not freeze |
| Safety Considerations | For intra-articular use only; not to be injected into infected/inflamed joints; safety in children not established |
| Attributes | Description |
|---|---|
| Manufacturer | Sanofi |
| Therapeutic Category | Orthopedic / Osteoarthritis Treatment |
| Composition | Hylan G-F 20, a high molecular weight hyaluronan derivative |
| Dosage Forms | Prefilled injectable syringes |
| Volume per Syringe | 2 mL or 6 mL |
| Intended Use | Treatment of knee OA pain and improving joint mobility |
| Recommended Dosage | One injection per week for 3 weeks or single injection of 6 mL |
| Contraindications | Infection or inflammation in target joint |
| Storage | Room temperature below 25°C, protect from light, do not freeze |
*Disclaimer: The above description has been AI-generated and has not been audited or verified for accuracy. It is recommended to verify product details independently before making any purchasing decisions.
SYNVISC® Injection is recommended primarily for patients with knee osteoarthritis who have not responded adequately to conservative treatments such as physiotherapy or oral analgesics. It is typically not used as a first-line therapy.
Administration must be performed intra-articularly by a trained physician into a non-infected and non-inflamed knee joint to avoid complications. Strict aseptic technique is essential.
SYNVISC® Injection is specifically indicated for the treatment of osteoarthritis knee pain. Use in other joints is not recommended without explicit physician guidance due to lack of established efficacy.
Synvisc-One provides a single 6 mL injection which offers similar relief and duration of effect as the three weekly 2 mL injections, providing convenience and compliance advantages.
SYNVISC® Injection should be stored at room temperature below 25°C, protected from light, and never frozen to ensure product stability.
Country Of Origin: India
Product Name: SYNVISC® Injection
Manufacturer: Sanofi
Composition: Hylan G-F 20 (a high molecular weight derivative of hyaluronan)
Therapeutic Category: Orthopedic / Osteoarthritis Treatment
Product Description: SYNVISC® is a viscosupplement used for the treatment of knee pain associated with osteoarthritis (OA) in patients who have not responded adequately to conservative treatments (e.g., physiotherapy, painkillers).
It is an injectable solution containing Hylan G-F 20, which mimics the natural hyaluronic acid found in synovial fluid. This helps restore lubrication and cushioning in the joints, thereby reducing pain and improving mobility.
Indications:
Mechanism of Action:
Dosage & Administration:
Packaging: Prefilled syringe: 2 mL or 6 mL (depending on regimen)
Storage:
Important Notes:
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