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SITAJAN MET 50/500 Tablet by Dr Precision is a specifically formulated fixed-dose combination therapy comprising Sitagliptin 50 mg and Metformin Hydrochloride 500 mg, strategically developed to enhance glycemic control in adults with type 2 diabetes mellitus. This dual-action oral hypoglycemic combines the DPP-4 inhibitory effect of Sitagliptin, which increases active incretin hormones promoting insulin secretion and suppressing glucagon post-meal, with Metformin’s capacity to reduce hepatic glucose production and improve peripheral insulin sensitivity. The synergy of these two agents targets both insulin resistance and impaired secretion, offering comprehensive blood glucose regulation while maintaining a low risk of hypoglycemia and neutral effect on body weight. Manufactured under stringent WHO-GMP, ISO 9001, and Schedule M standards by Bluepill Express in automated and quality-assured facilities, SITAJAN MET 50/500 ensures uniform dosage, stability, and safety. Administered twice daily with meals, it optimizes patient adherence and minimizes gastrointestinal tolerance issues. Its precision formulation, blister/alu-alu packaging, and availability for custom branding and export ensure this product is a reliable, high-quality solution tailored for professional healthcare providers and pharmaceutical distributors aiming to manage type 2 diabetes effectively through combination therapy.
Key Features
| Features | Description |
|---|---|
| Active Ingredients | Sitagliptin 50 mg and Metformin Hydrochloride 500 mg |
| Therapeutic Class | Oral Hypoglycemic Agent (DPP-4 Inhibitor + Biguanide) |
| Indication | Type 2 Diabetes Mellitus glycemic control |
| Mechanism of Action | Sitagliptin increases active incretins enhancing insulin release; Metformin decreases hepatic glucose output and improves insulin sensitivity |
| Dosage Form | Tablet |
| Administration | Oral, twice daily with meals |
| Manufacturing Standards | WHO-GMP, ISO 9001, Schedule M compliance in automated facilities |
| Packaging Type | Blister or Alu-Alu packaging for moisture and contamination protection |
| Quality Assurance | Strict raw material, in-process, and final product quality control |
| Additional Benefits | Low risk of hypoglycemia, weight neutral or modest weight loss |
| Attributes | Description |
|---|---|
| Brand | Dr Precision |
| Manufacturer | Bluepill Express |
| Composition | 50 mg Sitagliptin + 500 mg Metformin Hydrochloride per tablet |
| Formulation Type | Fixed-Dose Combination (FDC) |
| Storage Condition | Store in a cool, dry place away from direct sunlight |
| Shelf Life | Typically 24 months from manufacturing date |
| Packaging Options | Blister packs, Alu-Alu packs; custom branding & private labeling available |
| Intended Use | For adult patients with type 2 diabetes requiring improved glycemic control |
| Compliance Standards | WHO-GMP, ISO 9001, Schedule M |
| Administration Route | Oral |
*Disclaimer: The above description has been AI-generated and has not been audited or verified for accuracy. It is recommended to verify product details independently before making any purchasing decisions.
SITAJAN MET 50/500 provides enhanced glycemic control by combining Sitagliptin's incretin-based mechanism with Metformin's insulin sensitivity enhancement, targeting multiple pathophysiological defects in type 2 diabetes, thus offering superior efficacy compared to Metformin alone.
Sitagliptin increases active incretin levels only when blood glucose is elevated, stimulating insulin release and suppressing glucagon in a glucose-dependent manner, which lowers hypoglycemia risk unlike non-glucose-dependent hypoglycemic agents.
The tablets are manufactured in WHO-GMP, ISO 9001, and Schedule M compliant facilities with automated production processes including precision blending, granulation, and coating, supported by rigorous raw material and finished product quality control to ensure uniformity and safety.
Yes, Bluepill Express offers options for custom branding, export labeling, and private labeling, making SITAJAN MET 50/500 suitable for pharmaceutical distributors and exporters.
The product is available in blister or alu-alu packaging, which protects against moisture and contamination, ensuring prolonged shelf-life and stability under recommended storage conditions.
Country Of Origin: India
SITAJAN MET 50/500 Tablet is a combination of Sitagliptin (50 mg) and Metformin Hydrochloride (500 mg) designed to improve glycemic control in adults with type 2 diabetes mellitus. It brings together two complementary agents to address multiple aspects of blood glucose regulation. Manufactured by Bluepill Express under globally certified pharmaceutical facilities, SITAJAN MET 50/500 is a high-quality, reliable solution for diabetes care.
This product is manufactured under the Dr Precision label, ensuring GMP-compliant quality and precision formulation standards.
SITAJAN MET 50/500 Tablet is a dual-action oral hypoglycemic agent that combines Sitagliptin, a dipeptidyl peptidase-4 (DPP-4) inhibitor, with Metformin Hydrochloride, a biguanide antihyperglycemic agent. This fixed-dose combination has been developed to treat type 2 diabetes mellitus in adult patients who require enhanced glycemic control beyond Metformin monotherapy.
The 50 mg of Sitagliptin in SITAJAN MET enhances the body's natural ability to lower blood glucose by increasing levels of active incretin hormones. These hormones help stimulate insulin release and reduce glucagon secretion in response to meals, leading to better regulation of postprandial blood sugar. Sitagliptin is known for its glucose-dependent mechanism of action, which significantly reduces the risk of hypoglycemia and is weight-neutral.
Metformin Hydrochloride 500 mg, the second component, works primarily by reducing hepatic glucose production and increasing peripheral glucose uptake and utilization. It improves insulin sensitivity without increasing insulin secretion, thus addressing the insulin resistance component of type 2 diabetes. Metformin is also associated with modest weight loss or weight neutrality, which benefits overweight or obese diabetic patients.
SITAJAN MET 50/500 provides a synergistic therapeutic approach by combining these mechanisms. It is typically administered twice daily with meals to minimize gastrointestinal side effects and ensure optimal bioavailability. The dose is often titrated based on patient response and tolerability under a physician’s supervision.
This formulation is manufactured by Bluepill Express, adhering to WHO-GMP, ISO 9001, and Schedule M standards in fully compliant facilities equipped with automated manufacturing lines. The production process includes precision blending, granulation, tablet compression, and film coating, ensuring uniform drug content and prolonged stability.
Strict quality control protocols are followed at every stage—raw material testing, in-process checks, and final product analysis—to meet international regulatory requirements. The tablets are packed in blister or alu-alu packaging to ensure protection from moisture and contamination, with options available for custom branding, export labeling, and private labeling.
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Surat , India
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