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SITAJAN D 100/10 Tablet by Dr Precision is a premium fixed-dose combination formulation of Sitagliptin 100 mg and Metformin Hydrochloride Extended Release 1000 mg, designed specifically for adult patients with type 2 diabetes mellitus. This advanced oral antidiabetic medication offers synergistic dual action by combining Sitagliptin, a potent DPP-4 inhibitor, with Metformin ER, a biguanide featuring sustained release technology. Its mechanism strategically targets both fasting plasma glucose and postprandial glucose levels to optimize glycemic control. Manufactured by Bluepill Express under Dr Precision’s brand in WHO-GMP, ISO, and USFDA-standard facilities, SITAJAN D 100/10 ensures pharmaceutical-grade quality, safety, and efficacy. The extended-release Metformin component reduces gastrointestinal side effects while improving insulin sensitivity and lowering hepatic glucose production. Meanwhile, Sitagliptin enhances active incretin hormone levels glucose-dependently to promote insulin secretion and suppress glucagon secretion, minimizing hypoglycemia risk. Manufactured with cutting-edge granulation and coating methods, this tablet guarantees uniform drug distribution and a stable extended-release profile. SITAJAN D 100/10 is typically administered once daily with the evening meal, addressing nocturnal and early morning hyperglycemia effectively, and is ideal for patients inadequately controlled on Metformin monotherapy or exhibiting insulin resistance. It is supplied in blister or alu-alu strips to maintain product integrity and comply with global export standards, making it a trusted choice for hospital pharmacies, national diabetes care programs, and international distributors. Comprehensive regulatory documentation, including COA, COPP, stability data, and MSDS, accompanies the supply. SITAJAN D 100/10 exemplifies affordable, high-quality diabetic care, supporting improved patient compliance, and mitigated cardiovascular risk. Bluepill Express’ global export compliance and manufacturing precision make SITAJAN D 100/10 an optimal B2B pharmaceutical option for healthcare providers and distributors committed to effective diabetes management solutions.
Key Features
| Features | Description |
|---|---|
| Active Ingredients | Sitagliptin 100 mg + Metformin Hydrochloride Extended Release 1000 mg |
| Indication | Type 2 diabetes mellitus glycemic control |
| Mechanism of Action | DPP-4 inhibition by Sitagliptin; hepatic glucose reduction and enhanced insulin sensitivity by Metformin ER |
| Dosage Form | Film-coated extended-release tablet |
| Dosage Frequency | Once daily with the evening meal |
| Manufacturing Standards | WHO-GMP, ISO, USFDA compliant |
| Packaging | Alu-alu or blister strips |
| Regulatory Documentation | Certificate of Analysis (COA), Certificate of Pharmaceutical Product (COPP), Stability Data, MSDS |
| Target Patient Group | Adults with type 2 diabetes inadequately controlled with Metformin alone or insulin resistance |
| Global Market | Exported across Asia, Middle East, Africa, Latin America |
| Attributes | Description |
|---|---|
| Sitagliptin Content | 100 mg per tablet |
| Metformin Hydrochloride ER Content | 1000 mg per tablet |
| Tablet Weight | Approx. 1.5 g |
| Tablet Dimensions | Standard film-coated pill size for oral administration |
| Shelf Life | Minimum 24 months when stored properly |
| Storage Conditions | Store below 30°C, protect from moisture and light |
| Packaging Type | Blister pack or alu-alu strip (10 tablets per strip) |
| Compliance Standards | Manufactured under GMP and validated quality systems |
| Batch Testing | Identity, potency, purity, dissolution, stability, microbial & heavy metals free |
| Manufacturer | Bluepill Express under Dr Precision label |
*Disclaimer: The above description has been AI-generated and has not been audited or verified for accuracy. It is recommended to verify product details independently before making any purchasing decisions.
The extended-release Metformin in SITAJAN D 100/10 provides a sustained glucose-lowering effect that reduces dosing frequency and significantly lowers gastrointestinal side effects compared to immediate-release Metformin tablets, enhancing patient compliance.
Sitagliptin inhibits the DPP-4 enzyme, thereby increasing active incretin hormones in a glucose-dependent manner which enhances insulin secretion and suppresses glucagon only when blood glucose levels are elevated, thus minimizing the risk of hypoglycemia.
Yes, SITAJAN D 100/10 is indicated for adult patients including newly diagnosed individuals who require better glycemic control than Metformin monotherapy can achieve, especially in cases involving insulin resistance.
SITAJAN D 100/10 is manufactured under strict WHO-GMP, ISO, and USFDA-compliant conditions with validated analytical methods, ensuring identity, potency, purity, dissolution, stability, and freedom from microbial and heavy metal contamination.
The medication is best taken once daily with the evening meal, which effectively targets nocturnal and early morning glucose levels, improving overall glycemic control.
Yes, Bluepill Express offers custom labeling, international regulatory support, and logistics coordination to ensure SITAJAN D 100/10 meets specific market requirements and compliance for global export.
Country Of Origin: India
SITAJAN D Tablet is a fixed-dose combination of Sitagliptin and Metformin Hydrochloride (Extended Release). It is formulated for effective glycemic control in adult patients with type 2 diabetes mellitus, offering complementary mechanisms of action that target both fasting and postprandial blood glucose. Manufactured by Bluepill Express under stringent global standards, SITAJAN D provides high-quality, affordable diabetic care with global export compliance.
This product is manufactured under the Dr Precision label, ensuring GMP-compliant quality and precision formulation standards.
SITAJAN D Tablet is a scientifically developed oral antidiabetic formulation that combines the DPP-4 inhibitor Sitagliptin with the well-established biguanide Metformin Hydrochloride (Extended Release). This dual-action therapy is designed for adult patients with type 2 diabetes mellitus who require better glycemic control than achieved by monotherapy alone. The combination of Sitagliptin and Metformin targets different physiological pathways to provide a synergistic effect in lowering both fasting plasma glucose (FPG) and postprandial glucose (PPG) levels.
Sitagliptin enhances the levels of active incretin hormones by inhibiting the enzyme dipeptidyl peptidase-4 (DPP-4). This action increases insulin secretion and decreases glucagon levels in a glucose-dependent manner, resulting in improved glycemic control with minimal risk of hypoglycemia. Metformin, on the other hand, works by decreasing hepatic glucose production and improving insulin sensitivity at the cellular level. The extended-release formulation of Metformin provides sustained glucose-lowering effects and enhances patient compliance by reducing gastrointestinal side effects.
SITAJAN D is especially beneficial for newly diagnosed patients, those with a history of insulin resistance, or individuals who have not achieved adequate control on Metformin alone. It is usually prescribed as a once-daily tablet, preferably with the evening meal, allowing for better control of nighttime and early morning glucose levels. Clinical studies have shown that the combination improves HbA1c levels significantly while maintaining a favorable weight and cardiovascular risk profile.
The tablet is produced by Bluepill Express in WHO-GMP, ISO, and USFDA-standard facilities using advanced granulation and coating technologies to ensure uniform drug distribution and extended drug release. Strict in-process controls and validated analytical methods are employed to verify each batch for identity, potency, purity, dissolution, stability, and absence of microbial or heavy metal contamination.
SITAJAN D is offered in a range of strengths to accommodate patient-specific treatment plans. Available combinations typically include Sitagliptin 50 mg or 100 mg with Metformin ER 500 mg, 850 mg, or 1000 mg. Each tablet is packaged in alu-alu or blister strips to preserve product integrity and shelf life. Bluepill Express offers custom labeling, international regulatory support, and logistics coordination to ensure timely delivery and market compliance.
Our regulatory dossier includes Certificate of Analysis (COA), Certificate of Pharmaceutical Product (COPP), Stability Data, MSDS, and Site Master File. The SITAJAN D brand is exported to major markets in Asia, the Middle East, Africa, and Latin America. It is a trusted solution in national diabetes care programs and by hospital procurement authorities seeking cost-effective and reliable anti-diabetic medications.
Bluepill Express prioritizes therapeutic efficacy, affordability, and global standards in all its manufacturing operations. The development of SITAJAN D aligns with our mission to offer accessible treatments for chronic diseases like diabetes, which is increasing in prevalence worldwide. Through strategic partnerships with international distributors and government tenders, we ensure uninterrupted availability of SITAJAN D in high-demand markets.
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