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RABE AND DOM DSR CAPSULE by Bluepill Express under the Dr Precision label is a premium combination pharmaceutical product clinically designed to manage acid reflux, GERD, and related gastrointestinal disorders. This dual-action capsule uniquely combines Rabeprazole Sodium, a potent proton pump inhibitor (PPI), with Domperidone in a sustained-release format to deliver rapid, long-lasting relief from gastric acid hypersecretion and nausea while promoting enhanced gastric motility. Rabeprazole effectively inhibits the H⁺/K⁺ ATPase enzyme in gastric parietal cells, suppressing acid production critical for healing erosive esophagitis and reducing acid-induced damage and symptoms such as heartburn and regurgitation. The sustained-release Domperidone enhances gastrointestinal motility by blocking peripheral dopamine receptors, speeding gastric emptying and alleviating symptoms such as bloating, nausea, and fullness without crossing the blood-brain barrier, thereby minimizing central nervous system side effects. Manufactured in WHO-GMP and ISO-certified facilities with stringent quality controls including enteric coating for acid resistance and sustained-release granules for prolonged action, this capsule ensures high efficacy, safety, and patient compliance. Ideal for patients suffering from GERD, functional dyspepsia, gastroparesis, and other acid-related disorders, this combination therapy offers superior symptom management and faster relief compared to monotherapies. The product supports customizable branding and international regulatory compliance, making it suitable for pharmaceutical companies seeking a reliable, high-quality dual therapy solution for complex gastrointestinal conditions.
Key Features
| Features | Description |
|---|---|
| Active Ingredients | Rabeprazole Sodium (PPI) + Domperidone SR (Prokinetic and Antiemetic) |
| Mechanism of Action | Rabeprazole inhibits gastric acid secretion; Domperidone enhances gastric motility and reduces nausea |
| Formulation | Capsules with enteric-coated Rabeprazole pellets and sustained-release Domperidone granules |
| Indications | Treats GERD, acid reflux, functional dyspepsia, gastroparesis, chronic gastritis |
| Manufacturing Standards | Produced under WHO-GMP, ISO-certified facilities with rigorous quality checks |
| Dosage Form | Oral capsule, typically administered once daily before meals |
| Patient Compliance | Combination therapy reduces pill burden and enhances adherence |
| Side Effects | Generally well tolerated; may cause mild abdominal discomfort, headache, dry mouth |
| Export Compliance | Supports branded and generic labeling with full regulatory documentation (COA, COPP, CTD) |
| Stability | Stable across diverse climatic zones with proven shelf-life |
| Attributes | Description |
|---|---|
| Rabeprazole Sodium Content | 20 mg per capsule |
| Domperidone SR Content | 30 mg per capsule |
| Dosage Form | Capsule |
| Release Profile | Enteric-coated Rabeprazole; sustained-release Domperidone |
| Packaging | Available in blister packs or bottles as per client requirements |
| Shelf Life | 24 months from manufacturing date |
| Storage Conditions | Store in a cool, dry place away from direct sunlight |
| Regulatory Compliance | WHO-GMP, ISO, FDA-approved manufacturing process |
| Manufacturing Location | Bluepill Express certified facilities |
| Quality Control | Dissolution, assay, uniformity, and stability testing conducted |
| Indications | GERD, acid reflux, functional dyspepsia, gastroparesis, chronic gastritis |
*Disclaimer: The above description has been AI-generated and has not been audited or verified for accuracy. It is recommended to verify product details independently before making any purchasing decisions.
The sustained-release formulation ensures prolonged prokinetic and antiemetic action throughout the day, reducing dosing frequency and improving symptom control and patient compliance.
The enteric-coated Rabeprazole pellets undergo dissolution profiling that confirms acid-resistance and targeted intestinal release, ensuring optimal bioavailability and therapeutic effect.
Yes, Bluepill Express offers customizable packaging, branded or generic labeling, and provides comprehensive regulatory dossiers such as COA, COPP, and CTD for export compliance.
Combining Rabeprazole's acid suppression with Domperidone’s enhanced gastric motility addresses multiple pathophysiological aspects of GERD and related disorders, providing faster symptom relief and reducing overall medication burden.
Domperidone acts peripherally and does not significantly cross the blood-brain barrier, which reduces the risk of central nervous system adverse effects such as extrapyramidal symptoms.
The product has undergone rigorous stability evaluations demonstrating maintained potency and quality across various temperature and humidity conditions, ensuring safe storage and effective shelf life in multiple markets.
Country Of Origin: India
RABE AND DOM DSR CAPSULE is a clinically effective combination of Rabeprazole Sodium and Domperidone SR, formulated to manage acid reflux, GERD, and other gastrointestinal disorders. Manufactured by Bluepill Express under strict global standards, this dual-action therapy offers rapid relief from hyperacidity and nausea while enhancing gastric motility.
This product is manufactured under the Dr Precision label, ensuring GMP-compliant quality and precision formulation standards.
RABE AND DOM DSR CAPSULE by Bluepill Express is a combination pharmaceutical product designed to treat various upper gastrointestinal disorders, including gastroesophageal reflux disease (GERD), functional dyspepsia, and chronic gastritis. This capsule features a unique dual mechanism of action by combining Rabeprazole Sodium, a proton pump inhibitor (PPI), with Domperidone, a dopamine D2 receptor antagonist with prokinetic and antiemetic properties.
Rabeprazole Sodium in this formulation works by irreversibly inhibiting the H⁺/K⁺ ATPase enzyme in the gastric parietal cells, effectively blocking the final step of acid production in the stomach. It provides potent and long-lasting reduction of gastric acid secretion, which is essential in the healing of erosive esophagitis and peptic ulcers. It also helps prevent acid-related damage to the esophageal lining and provides symptomatic relief from heartburn and regurgitation.
Domperidone, included in a sustained-release format, enhances gastrointestinal motility and accelerates gastric emptying. By blocking dopamine receptors in the chemoreceptor trigger zone and the upper digestive tract, it reduces symptoms like nausea, bloating, and a feeling of fullness. Its peripheral action helps it avoid crossing the blood-brain barrier, which minimizes central nervous system side effects.
This capsule is especially useful for patients with GERD, gastroparesis, and non-ulcer dyspepsia, where both acid suppression and prokinetic therapy are needed. It is commonly prescribed in morning doses, preferably before meals, to provide full-day symptom control. The combination therapy offers enhanced patient compliance and faster relief compared to monotherapy regimens.
Bluepill Express manufactures RABE AND DOM DSR CAPSULES in world-class facilities certified by WHO-GMP, ISO, and other international regulatory bodies. The product is developed using enteric-coated pellets of Rabeprazole to ensure acid resistance and optimal release in the intestine, along with sustained-release granules of Domperidone for extended prokinetic action.
Each capsule undergoes rigorous quality checks including dissolution profiling, assay testing, uniformity, and stability evaluation to ensure safety, efficacy, and shelf-life across diverse climatic zones. Our third-party and contract manufacturing model ensures customizable solutions for partners, including branded and generic labeling, international export compliance, and batch-specific documentation such as COA, COPP, and CTD dossiers.
RABE AND DOM DSR CAPSULES are well tolerated by most patients, but like all medications, they may occasionally cause side effects such as headache, dry mouth, abdominal cramps, or mild diarrhea. Rare but serious adverse effects include galactorrhea or extrapyramidal symptoms, particularly with prolonged Domperidone use, necessitating periodic clinical review.
With increasing cases of acid-peptic disorders due to stress, irregular diet, and lifestyle changes, there is a growing demand for combination therapies that address multiple GI symptoms in a single formulation. RABE AND DOM DSR CAPSULES by Bluepill Express are positioned to meet this clinical demand through precise formulation, high-quality ingredients, and internationally certified production.
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Surat , India
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