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The Pregabalin 75mg + Nortriptyline HCI 10mg + Methylcobalamin 1500mcg Tablet is a specialized combination medication designed for effective management of neuropathic pain and associated neurological symptoms. This tablet combines three potent active ingredients: Pregabalin, Nortriptyline HCl, and Methylcobalamin, each providing targeted action against nerve-related pain disorders. Pregabalin acts as an anticonvulsant and analgesic by stabilizing nerve activity and reducing the transmission of pain signals via calcium channel modulation. Nortriptyline, a tricyclic antidepressant, complements this effect by inhibiting the reuptake of serotonin and norepinephrine, thereby enhancing pain modulation pathways. Methylcobalamin, a bioactive form of Vitamin B12, supports the regeneration and repair of damaged nerves and the myelin sheath, promoting nerve health and function. This potent combination is particularly effective in conditions such as diabetic peripheral neuropathy, sciatica, post-herpetic neuralgia, radiculopathy, and other chronic nerve-related pain disorders. The tablet is generally prescribed for use once or twice daily after meals, optimizing patient adherence and minimizing side effects. With this combination, healthcare providers can offer patients significant relief from neuropathic pain symptoms including burning, tingling, numbness, and chronic discomfort, improving quality of life. Side effects are usually mild and can include dizziness, dry mouth, constipation, and infrequent blurred vision. This product is a vital pharmaceutical solution for medical professionals managing complex neuropathic pain cases in clinical settings.
Key Features
| Features | Description |
|---|---|
| Active Ingredients | Pregabalin 75mg, Nortriptyline HCI 10mg, Methylcobalamin 1500mcg |
| Therapeutic Uses | Management of neuropathic pain, diabetic peripheral neuropathy, sciatica, post-herpetic neuralgia, radiculopathy |
| Mechanism of Action | Pregabalin reduces nerve pain via calcium channel binding; Nortriptyline inhibits serotonin and norepinephrine reuptake; Methylcobalamin aids nerve regeneration |
| Dosage Form | Tablet |
| Dosage Instructions | Typically once or twice daily, preferably after meals as directed by physician |
| Potency | 75mg Pregabalin, 10mg Nortriptyline HCl, 1500mcg Methylcobalamin per tablet |
| Side Effects | Mild dizziness, drowsiness, dry mouth, constipation, rare blurred vision |
| Indications | Neuropathic pain disorders including nerve injury-related pain, neuralgia, and paresthesia |
| Therapeutic Benefits | Effective relief from nerve-related symptoms like burning, numbness, tingling |
| Regeneration Support | Contains Methylcobalamin to promote nerve repair and myelin sheath regeneration |
| Attributes | Description |
|---|---|
| Pregabalin Strength | 75mg |
| Nortriptyline HCl Strength | 10mg |
| Methylcobalamin Strength | 1500mcg |
| Pharmacological Class | Anticonvulsant, Tricyclic Antidepressant, Neurotropic Vitamin |
| Formulation Type | Oral tablet |
| Therapeutic Indications | Neuropathic pain, diabetic neuropathy, radiculopathy, post-herpetic neuralgia |
| Administration Route | Oral |
| Frequency | Once or twice daily |
| Storage Conditions | Store in a cool, dry place away from direct sunlight |
| Shelf Life | As per manufacturer guidelines |
*Disclaimer: The above description has been AI-generated and has not been audited or verified for accuracy. It is recommended to verify product details independently before making any purchasing decisions.
This tablet is specifically formulated to treat neuropathic pain conditions such as diabetic peripheral neuropathy, sciatica, post-herpetic neuralgia, radiculopathy, nerve injury-related pain, and other chronic nerve-related pain disorders.
Methylcobalamin supports nerve repair by promoting regeneration of damaged nerves and regeneration of the myelin sheath, which is essential for restoring nerve function and decreasing neuropathic symptoms.
Yes, the combination of Pregabalin and Nortriptyline provides analgesic and pain-modulating effects effective for both acute flare-ups and long-term management of chronic neuropathic pain.
The tablet is recommended to be taken once or twice daily preferably after meals to enhance absorption and minimize gastrointestinal side effects. The exact dosage should be prescribed based on patient condition.
Clinicians should monitor for mild dizziness, drowsiness, dry mouth, constipation, and rare instances of blurred vision to ensure patient safety and make dosage adjustments if needed.
Brand: stallion
Country Of Origin: India
This combination tablet is used for the management of neuropathic pain and associated neurological symptoms.
Pregabalin is an anticonvulsant and analgesic that reduces nerve pain.
Nortriptyline is a tricyclic antidepressant with pain-modulating properties.
Methylcobalamin is a neurotropic vitamin that helps regenerate damaged nerves.
Together, they provide effective relief from nerve-related pain, tingling, numbness, and burning sensations commonly seen in conditions like diabetic neuropathy and sciatica.
Indications:
Diabetic peripheral neuropathy
Neuropathic pain (sciatica, post-herpetic neuralgia, radiculopathy)
Nerve injury-related pain
Neuralgia and paresthesia
Chronic nerve-related pain disorders
Mechanism of Action:
Pregabalin: Binds to calcium channels in nerve cells to reduce pain signal transmission.
Nortriptyline: Inhibits reuptake of serotonin and norepinephrine, enhancing pain modulation.
Methylcobalamin: Supports nerve repair and myelin sheath regeneration.
Dosage:
As directed by the physician, usually once or twice daily, preferably after meals.
Side Effects (Common & Usually Mild):
Dizziness or drowsiness
Dry mouth
Constipation
Weight gain (in some patients)
Blurred vision (rare)
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