PHAGE GP 2 TAB by Dr Precision is a sophisticated dual oral antidiabetic medication tailored specifically for the management of Type 2 Diabetes Mellitus. This fixed-dose combination tablet integrates Glimepiride 2 mg, a potent sulfonylurea that stimulates insulin release from pancreatic β-cells, with Metformin Hydrochloride 500 mg in a sustained-release form that enhances insulin sensitivity and reduces hepatic glucose production. The dual mechanism ensures comprehensive glycemic control, targeting both fasting and postprandial glucose levels while decreasing HbA1c values effectively. Manufactured by Bluepill Express in globally certified GMP, WHO-GMP, ISO, and HACCP compliant facilities, PHAGE GP 2 TAB guarantees high production standards, uniformity, and stability for domestic and international markets. The sustained-release matrix of Metformin ensures gradual absorption, significantly reducing gastrointestinal side effects typically associated with Metformin immediate release formulations, thus improving patient adherence. This formulation is ideal for patients inadequately controlled on monotherapy and requiring combination therapy for enhanced glucose regulation. PHAGE GP 2 TAB minimizes pill burden by combining two complementary antidiabetic agents in a single tablet, administered once daily with meals to optimize efficacy while reducing hypoglycemia risks. Bluepill Express supports private labeling, custom packaging, and provides extensive regulatory documentation, accommodating diverse pharmacopeial and export standards. Overall, PHAGE GP 2 TAB offers a reliable, quality-assured solution for healthcare providers seeking effective glycemic management in adult Type 2 Diabetes patients needing advanced therapeutic intervention.
Key Features
| Features | Description |
|---|---|
| Active Ingredients | Glimepiride 2 mg and Metformin Hydrochloride 500 mg (Sustained Release) |
| Therapeutic Use | Management of Type 2 Diabetes Mellitus |
| Mechanism of Action | Insulinotropic action of Glimepiride and insulin-sensitizing effect of sustained-release Metformin |
| Formulation Type | Fixed-dose dual oral antidiabetic tablet |
| Dosage Form | Sustained Release tablet |
| Manufacturer | Bluepill Express under Dr Precision label |
| Quality Standards | WHO-GMP, ISO, HACCP compliance with rigorous quality checks |
| Patient Compliance | Once-daily dosing with reduced gastrointestinal side effects |
| Packaging & Customization | Supports private labeling, custom packaging, and international documentation |
| Contraindications | Not for Type 1 Diabetes, renal impairment, hepatic dysfunction, or sulfonylurea/Metformin hypersensitivity |
| Attributes | Description |
|---|---|
| Glimepiride Content | 2 mg per tablet |
| Metformin Hydrochloride Content | 500 mg sustained-release per tablet |
| Release Profile | Sustained release for Metformin ensuring steady plasma levels |
| Indicated For | Adult patients with Type 2 Diabetes Mellitus requiring combination therapy |
| Administration | Oral, once daily with main meals (preferably breakfast or lunch) |
| Manufacturing Standards | Produced under WHO-GMP, ISO, HACCP standards with stability testing |
| Stability Profile | Real-time and accelerated stability validated |
| Pharmacopoeial Compliance | Customizable to IP, BP, USP or client-specific standards |
| Safety Profile | Well tolerated with mild initial GI effects, hypoglycemia risk managed by titration |
| Packaging | Available with private label and export documentation support |
*Disclaimer: The above description has been AI-generated and has not been audited or verified for accuracy. It is recommended to verify product details independently before making any purchasing decisions.
The sustained-release matrix of Metformin ensures gradual absorption throughout the day, significantly reducing gastrointestinal side effects such as nausea and bloating. This improved tolerability encourages consistent daily use, enhancing patient compliance compared to immediate-release formulations.
PHAGE GP 2 TAB combines Glimepiride’s insulinotropic effect with Metformin’s insulin-sensitizing action, providing a dual mechanism for glucose regulation. This combination addresses multiple metabolic pathways, resulting in better glycemic control for patients who do not achieve target blood sugar levels with single-agent therapy.
PHAGE GP 2 TAB undergoes stringent quality control including in-process and post-production testing like dissolution, assay validation, impurity profiling, and stability tests (both real-time and accelerated). Manufactured in WHO-GMP, ISO, and HACCP certified plants, these measures ensure consistent product quality and patient safety.
Yes, Bluepill Express provides customization of PHAGE GP 2 TAB to comply with various pharmacopeial standards such as IP, BP, USP, or other client-specific requirements, facilitating global market accessibility.
To reduce hypoglycemia risk, careful dose titration of Glimepiride is essential alongside adherence to prescribed mealtimes. Patient education regarding symptom recognition and consistent administration with meals further mitigates potential hypoglycemic episodes.
No, PHAGE GP 2 TAB is contraindicated in patients with renal impairment and hepatic dysfunction due to altered drug metabolism and increased risk of adverse effects.
Country Of Origin: India
PHAGE GP 2 TAB is a dual oral antidiabetic formulation combining Glimepiride 2 mg and Metformin Hydrochloride 500 mg (Sustained Release). It is designed for the effective management of Type 2 Diabetes Mellitus by combining insulinotropic and insulin-sensitizing mechanisms. Manufactured by Bluepill Express under internationally accredited facilities, it ensures consistent glycemic control, high safety standards, and global export readiness.
This product is manufactured under the Dr Precision label, ensuring GMP-compliant quality and precision formulation standards.
PHAGE GP 2 TAB is an advanced oral antidiabetic combination medication formulated to offer comprehensive glycemic control in patients diagnosed with Type 2 Diabetes Mellitus. It contains Glimepiride 2 mg and Metformin Hydrochloride 500 mg in a sustained-release matrix, synergistically working to reduce blood glucose levels through multiple metabolic pathways. This fixed-dose combination is especially suitable for patients who have not achieved sufficient glucose regulation through monotherapy and require escalation of treatment.
Glimepiride is a modern sulfonylurea that functions by enhancing the release of insulin from pancreatic β-cells. With a relatively longer half-life and high binding affinity to pancreatic receptors, Glimepiride provides stable and sustained insulinotropic action, reducing postprandial glucose spikes. The 2 mg dose in PHAGE GP 2 TAB is considered optimal for patients requiring moderate to advanced insulin stimulation, particularly those with suboptimal HbA1c values on lower-dose regimens.
Metformin, a biguanide-class agent, complements Glimepiride by improving insulin sensitivity and reducing hepatic glucose production. The 500 mg sustained-release component in this formulation ensures prolonged absorption and a steady plasma concentration of Metformin throughout the day. This delivery system significantly reduces the incidence of gastrointestinal disturbances typically associated with immediate-release Metformin while enhancing patient compliance.
Manufactured by Bluepill Express in internationally compliant facilities, PHAGE GP 2 TAB adheres to strict WHO-GMP, ISO, and HACCP standards. The product undergoes comprehensive in-process and post-production quality checks including dissolution studies, assay validation, impurity profiling, and real-time and accelerated stability testing. These processes ensure high therapeutic consistency, uniformity, and product integrity—making PHAGE GP 2 TAB suitable for both domestic and global distribution.
The formulation is ideal for adult patients with Type 2 Diabetes who require combination therapy to maintain target glycemic levels. It helps reduce both fasting plasma glucose and postprandial glucose values, while also contributing to HbA1c reduction over time. By combining the actions of two agents in a single tablet, PHAGE GP 2 TAB minimizes pill burden, improves compliance, and optimizes outcomes in diabetes care.
This tablet is typically administered once daily with the main meal, preferably breakfast or lunch, to coincide with peak insulin requirements and to mitigate the risk of hypoglycemia. The sustained-release matrix of Metformin facilitates prolonged glucose control, while Glimepiride’s rapid action covers immediate postprandial needs.
Bluepill Express offers full support for private labeling, custom packaging, and international documentation, including product dossiers, COAs, batch manufacturing records, and export-oriented technical files. The product can be customized for regional pharmacopeial standards including IP, BP, USP, or customized specifications based on client needs.
PHAGE GP 2 TAB is generally well tolerated. Common side effects may include mild gastrointestinal disturbances such as nausea or bloating in the initial days of therapy. Hypoglycemia is a potential concern with sulfonylureas but can be minimized with careful dose titration, adherence to prescribed meal timing, and proper patient education. The product is contraindicated in patients with Type 1 Diabetes, renal impairment, hepatic dysfunction, or known hypersensitivity to sulfonylureas or Metformin.
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