PHAGE GP 1 TAB by Dr Precision is a specialized fixed-dose oral antidiabetic formulation combining Metformin Hydrochloride 500 mg (sustained release) and Glimepiride 1 mg (immediate release) designed specifically for effective, sustained glycemic control in patients with Type 2 Diabetes Mellitus. This combination tablet works through dual mechanisms: Metformin enhances insulin sensitivity and reduces hepatic glucose production with its time-released formula, minimizing gastrointestinal side effects and promoting adherence; Glimepiride stimulates pancreatic beta-cell insulin release quickly, with a low risk of hypoglycemia and minimal weight gain. Manufactured by Bluepill Express under stringent WHO-GMP, ISO, and HACCP standards, PHAGE GP 1 TAB undergoes comprehensive quality assurance ensuring batch-to-batch consistency and therapeutic reliability. Ideal for patients inadequately controlled by diet, exercise, or monotherapy, it simplifies diabetes management by reducing pill burden while offering superior HbA1c reduction benefits. The product is supplied in customizable packaging with full regulatory documentation support for easy international market access. PHAGE GP 1 TAB is prescribed once daily with meals, providing a tailored balance of fast-acting and extended-release antidiabetic action, optimized for safety, efficacy, and improved patient compliance in Type 2 Diabetes management.
Key Features
| Features | Description |
|---|---|
| Active Ingredients | Metformin Hydrochloride 500 mg (sustained release), Glimepiride 1 mg (immediate release) |
| Therapeutic Use | Management of Type 2 Diabetes Mellitus with inadequate glycemic control on monotherapy |
| Mechanism of Action | Metformin reduces hepatic glucose production and improves insulin sensitivity; Glimepiride stimulates insulin secretion from pancreatic beta cells |
| Dosage Form | Oral tablet, fixed-dose combination, sustained release Metformin and immediate release Glimepiride |
| Manufacturing Standards | WHO-GMP, ISO, HACCP certified production ensuring quality and regulatory compliance |
| Quality Assurance | In-process checks, dissolution profiling, stability testing, analytical validation |
| Packaging Options | Customizable packaging including alu-alu blisters and HDPE bottles with private labeling |
| Administration | Once daily with the first main meal to maximize efficacy and reduce side effects |
| Safety Profile | Minimized gastrointestinal side effects due to sustained release; low hypoglycemia risk with Glimepiride 1 mg dose |
| Regulatory Support | Comprehensive documentation including Certificates of Analysis and Stability Reports for international registration |
| Attributes | Description |
|---|---|
| Metformin Hydrochloride Content | 500 mg (sustained release) |
| Glimepiride Content | 1 mg (immediate release) |
| Indication | Type 2 Diabetes Mellitus requiring combination therapy |
| Pharmacokinetics | Sustained release Metformin for gradual effect; immediate release Glimepiride for rapid insulin secretion |
| Shelf Life | As per stability data, typically 24 months under recommended storage conditions |
| Storage Conditions | Store in a cool, dry place away from direct sunlight |
| Contraindications | Severe renal impairment, hepatic dysfunction, sulfonylurea hypersensitivity |
| Side Effects | Mild gastrointestinal symptoms initially; minimal hypoglycemia risk |
| Manufacturer | Bluepill Express under Dr Precision label |
| Certifications | WHO-GMP, ISO, HACCP |
*Disclaimer: The above description has been AI-generated and has not been audited or verified for accuracy. It is recommended to verify product details independently before making any purchasing decisions.
The sustained release form of Metformin in PHAGE GP 1 TAB ensures gradual drug release over time, which minimizes common gastrointestinal side effects such as nausea or diarrhea. This improved tolerability enhances patient compliance with once-daily dosing.
Glimepiride at 1 mg immediate release provides rapid stimulation of pancreatic insulin secretion, complementing the prolonged insulin sensitizing effect of Metformin, thereby offering effective round-the-clock glycemic control while reducing the incidence of hypoglycemia.
Bluepill Express supplies PHAGE GP 1 TAB in customizable packaging formats such as alu-alu blister packs and HDPE bottles with options for private labeling and multilingual packaging to meet international market requirements.
The manufacturing of PHAGE GP 1 TAB adheres to WHO-GMP, ISO, and HACCP certifications, ensuring high-quality, safe, and consistent product batches compliant with international regulatory standards.
PHAGE GP 1 TAB is contraindicated in patients with severe renal impairment due to the risk of Metformin-associated lactic acidosis, and careful patient assessment is recommended before prescribing.
Country Of Origin: India
PHAGE GP 1 TAB is a combination oral antidiabetic medication containing Metformin Hydrochloride (500 mg, sustained release) and Glimepiride (1 mg). Designed for effective management of Type 2 Diabetes Mellitus, it improves insulin sensitivity and stimulates pancreatic insulin release. Manufactured by Bluepill Express under international quality standards, this formulation offers reliable glycemic control with optimal patient compliance.
This product is manufactured under the Dr Precision label, ensuring GMP-compliant quality and precision formulation standards.
PHAGE GP 1 TAB is a dual-action oral antidiabetic formulation developed for effective and sustained glycemic control in patients suffering from Type 2 Diabetes Mellitus. This tablet combines two well-established antidiabetic agents: Metformin Hydrochloride 500 mg in a sustained-release form and Glimepiride 1 mg in an immediate-release form. This combination provides complementary mechanisms of action that target multiple aspects of glucose metabolism, making it ideal for patients who require combination therapy for optimal diabetes management.
Metformin, a biguanide class agent, primarily works by reducing hepatic glucose production, enhancing peripheral glucose uptake, and improving insulin sensitivity. It is especially beneficial in overweight and insulin-resistant individuals and is globally recognized as the first-line therapy in Type 2 diabetes. The sustained-release profile in PHAGE GP 1 TAB ensures a gradual and consistent release of Metformin throughout the day, thereby minimizing gastrointestinal side effects and improving patient adherence.
Glimepiride, a second-generation sulfonylurea, acts by stimulating insulin release from pancreatic beta cells. It has a rapid onset and long duration of action and is known for causing less weight gain and hypoglycemia compared to older sulfonylureas. The 1 mg dose in this combination is well-suited for patients initiating dual therapy or those with moderate glucose elevation despite Metformin monotherapy.
PHAGE GP 1 TAB is manufactured by Bluepill Express in advanced WHO-GMP, ISO, and HACCP-certified facilities that meet stringent international regulatory requirements. The formulation undergoes rigorous quality assurance processes including in-process checks, dissolution profiling, stability testing, and analytical validation. This ensures consistency, therapeutic reliability, and safety in every batch shipped for domestic or international use.
This tablet is indicated for adults with Type 2 Diabetes who do not achieve adequate glycemic control with diet, exercise, or monotherapy alone. It is frequently prescribed as a step-up treatment after Metformin monotherapy or as a maintenance therapy in stable patients requiring combined glycemic regulation. The fixed-dose combination improves compliance by reducing pill burden and offers synergistic benefits that help lower HbA1c more effectively than individual agents.
PHAGE GP 1 TAB is typically administered once daily with the first main meal to maximize its therapeutic benefits and reduce gastrointestinal discomfort. The pharmacokinetic compatibility between the sustained-release Metformin and fast-acting Glimepiride supports a consistent glucose-lowering effect throughout the day without excessive risk of hypoglycemia.
Bluepill Express offers PHAGE GP 1 TAB in customized packaging solutions such as alu-alu blisters or HDPE bottles, with private labeling, multilingual pack support, and all necessary documentation for international registrations including Certificate of Analysis, Batch Manufacturing Record, Stability Reports, and Dossiers. The product can be tailored to comply with the pharmacopeial and regulatory standards of importing countries.
The safety profile of PHAGE GP 1 TAB is well-established. Mild gastrointestinal side effects like nausea, flatulence, or diarrhea may occur initially, mainly due to Metformin. Glimepiride-associated risks like hypoglycemia are mitigated by the careful dosing strategy and the once-daily administration format. It is contraindicated in patients with severe renal impairment, hepatic dysfunction, or known sulfonylurea hypersensitivity.
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