N-Bromosuccinimide (NBS) is a highly efficient brominating and oxidizing agent specifically formulated for advanced organic synthesis applications. With its stable solid form, NBS enables precise allylic and benzylic bromination under controlled, mild reaction conditions, making it indispensable for chemists focusing on free-radical mechanisms. Its unique chemical properties make it an ideal reagent in the pharmaceutical and agrochemical industries for synthesizing active pharmaceutical ingredients (APIs) and bioactive compounds. Additionally, NBS serves as a mild oxidant in oxidative cyclization reactions, contributing to selective transformations in complex molecular architectures. Packaged in 25 kg fiber drums, it caters to large scale laboratory and industrial demands, ensuring consistent quality and reliable performance. NBS is readily soluble in organic solvents like acetone and acetonitrile, enhancing its versatility in reaction setups. Proper storage in cool, dark environments preserves its integrity, while its oxidizing nature warrants careful handling to prevent irritation. Overall, NBS stands out as a crucial reagent for chemical manufacturers and research entities involved in cutting-edge organic synthesis and process development.
Key Features
| Features | Description |
|---|---|
| Chemical Nature | Stable solid brominating and oxidizing agent |
| Primary Application | Selective allylic and benzylic bromination |
| Reaction Conditions | Mild and controlled environment suitable for free-radical reactions |
| Industries Served | Pharmaceutical, agrochemical, and specialty chemical manufacturing |
| Packaging | 25 kg fiber drum suitable for bulk use |
| Solubility | Soluble in acetone and acetonitrile |
| Oxidizing Agent | Acts as a mild oxidizer in oxidative cyclizations |
| Handling and Storage | Store in cool, dark place; oxidizing, may cause irritation |
| CAS Number | 128-08-5 |
| Molecular Weight | 177.98 g/mol |
| Attributes | Description |
|---|---|
| Molecular Formula | C4H4BrNO2 |
| Physical State | Stable solid |
| Bromination Selectivity | Allylic and benzylic positions |
| Compatibility | Compatible with various solvents such as acetone and acetonitrile |
| Toxicity | Oxidizing agent; may cause skin and respiratory irritation |
| Storage Conditions | Cool, dark place away from incompatible substances |
| Packaging Details | Bulk 25 kg fiber drum |
| Synonyms | NBS, N-Bromo succinimide |
*Disclaimer: The above description has been AI-generated and has not been audited or verified for accuracy. It is recommended to verify product details independently before making any purchasing decisions.
N-Bromosuccinimide’s structure and stability allow it to selectively brominate allylic and benzylic positions through free-radical mechanisms under mild reaction conditions, minimizing side reactions.
NBS should be stored in a cool, dark place to prevent decomposition and maintain its oxidizing properties, ensuring consistent performance during large-scale synthesis.
Yes, apart from bromination, NBS acts as a mild oxidizing agent facilitating oxidative cyclization steps essential in the synthesis of complex organic molecules.
N-Bromosuccinimide is readily soluble in organic solvents like acetone and acetonitrile, allowing for facile use in a variety of reaction conditions.
Due to its oxidizing nature, NBS should be handled with appropriate personal protective equipment to prevent irritation and avoid exposure to incompatible materials.
Country Of Origin: India
N-Bromosuccinimide is a brominating and oxidizing agent widely used in organic chemistry for allylic and benzylic bromination. As a stable solid, NBS allows selective introduction of bromine atoms under mild conditions. It’s especially useful in free-radical reactions and in the synthesis of pharmaceuticals and agrochemicals. NBS also acts as a mild oxidizer in some oxidative cyclizations.
Product Summary:
CAS Number: 128-08-5
Molecular Formula: C4H4BrNO2
Molecular Weight: 177.98 g/mol
Synonyms: NBS
Packaging: 25 kg fiber drum
Solubility: Soluble in acetone, acetonitrile
Storage: Store in a cool, dark place
Toxicity: Oxidizing; can cause irritation
Applications:
Bromination of organic compounds
Radical initiator and oxidizer
Intermediate in synthesis of APIs
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