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ES-PROZOLE DSR TAB by Dr Precision is a dual-release gastro-protective tablet combining Esomeprazole 40 mg and Domperidone 30 mg, designed specifically to treat acid reflux, gastroesophageal reflux disease (GERD), functional dyspepsia, and associated gastrointestinal motility disorders. This advanced DSR (Dual Sustained Release) formulation utilizes enteric-coated Esomeprazole granules to bypass stomach acid and ensure targeted absorption in the intestine, delivering potent proton pump inhibition for prolonged acid suppression. Concurrently, Domperidone in sustained-release form enhances gastrointestinal motility by antagonizing dopamine D2 receptors, aiding gastric emptying and reducing symptoms such as nausea, vomiting, bloating, and abdominal discomfort. Perfect for third-party pharma manufacturing, hospital supply, and international export, ES-PROZOLE DSR TAB guarantees consistent 24-hour symptom relief with superior bioavailability and optimized patient compliance. Manufactured under strict WHO-GMP and Dr Precision's quality standards by BluepillExpress, this tablet offers a frontline solution for acid peptic disorders requiring both acid suppression and prokinetic support.
Key Features
| Features | Description |
|---|---|
| Active Ingredients | Esomeprazole 40 mg and Domperidone 30 mg |
| Dual Release Technology | Enteric-coated Esomeprazole granules for delayed intestinal absorption and sustained-release Domperidone |
| Therapeutic Benefits | Effective acid suppression combined with enhanced gastrointestinal motility |
| Indications | GERD, acid peptic disorders, functional dyspepsia, chronic gastritis, delayed gastric emptying, nausea and vomiting |
| Dosage Form | Oral dual sustained-release tablet |
| Duration of Action | Provides up to 24 hours of symptom relief |
| Manufacturer | BluepillExpress under Dr Precision label |
| Compliance & Quality | Formulated under WHO-GMP certifications with advanced pelletization and coating technology |
| Application | Ideal for third-party pharma manufacturing, hospital supply, and international distribution |
| Attributes | Description |
|---|---|
| Esomeprazole Content | 40 mg per tablet (enteric-coated) |
| Domperidone Content | 30 mg per tablet (sustained-release) |
| Formulation Technology | Dual Sustained Release (DSR) with pelletization and coating |
| Intended Use | Management of acid reflux, GERD, functional dyspepsia, and gastric motility disorders |
| Administration Route | Oral |
| Recommended Dosage | One tablet daily, 30 minutes before breakfast on an empty stomach |
| Packaging | Blister packs customizable for bulk pharma supply |
| Manufacturing Standards | WHO-GMP certified production |
| Storage Conditions | Store in a cool, dry place, protected from moisture and heat |
| Shelf Life | 24 months from the date of manufacture |
*Disclaimer: The above description has been AI-generated and has not been audited or verified for accuracy. It is recommended to verify product details independently before making any purchasing decisions.
The dual-release technology ensures that Esomeprazole, the acid suppressant, is released in the intestine via an enteric coating for targeted absorption, while Domperidone is released in a sustained manner to maintain therapeutic levels. This results in rapid onset and prolonged 24-hour relief from acid-related symptoms and improved gastric motility, enhancing overall efficacy and patient compliance.
ES-PROZOLE DSR TAB is manufactured under WHO-GMP certified processes with advanced pelletization and coating technology, ensuring high quality, bioequivalence, and consistent therapeutic effects. Its stable shelf life and customizable blister packaging make it ideal for large-scale pharma production and export.
Yes, the Domperidone component in ES-PROZOLE DSR TAB acts as a prokinetic by antagonizing dopamine D2 receptors, promoting faster gastric emptying, and thereby effectively reducing nausea, vomiting, and bloating associated with delayed gastric emptying.
The tablet should be taken orally on an empty stomach, preferably 30 minutes before breakfast once daily. This timing optimizes Esomeprazole absorption and maximizes acid suppression and symptom control throughout the day.
Yes, the unique combination of Esomeprazole for acid suppression and Domperidone for prokinetic action delivers comprehensive management of acid reflux symptoms alongside improvement in gastrointestinal motility, making it effective for multiple related conditions such as GERD, functional dyspepsia, and gastric stasis.
Country Of Origin: India
ES-PROZOLE DSR TAB is a combination gastro-protective formulation containing Esomeprazole 40 mg and Domperidone 30 mg, engineered in dual-release technology to treat acid reflux, GERD, and functional dyspepsia. Esomeprazole suppresses gastric acid production while Domperidone acts as a prokinetic, enhancing gastrointestinal motility and controlling nausea. Manufactured by BluepillExpress, this DSR (Dual Sustained Release) tablet ensures both rapid and extended symptom relief. Ideal for third-party pharma manufacturing, hospital supply, and international distribution, ES-PROZOLE DSR is widely accepted in gastroenterology practices.
This product is manufactured under the Dr Precision label, ensuring GMP-compliant quality and precision formulation standards.
ES-PROZOLE DSR TAB, manufactured by BluepillExpress, is a scientifically advanced, dual-layered gastroenterological tablet combining the powerful proton pump inhibition of Esomeprazole with the prokinetic and antiemetic action of Domperidone. It is specially designed to offer long-lasting relief from acid-related disorders such as gastroesophageal reflux disease (GERD), non-ulcer dyspepsia, gastritis, and nausea-vomiting associated with delayed gastric emptying.
This formulation combines Esomeprazole 40 mg, delivered as enteric-coated granules, ensuring it bypasses the stomach for targeted intestinal absorption, and Domperidone 30 mg, provided in a sustained-release format to maintain therapeutic levels over an extended period. This dual-release action ensures both immediate symptom control and prolonged acid suppression for a full 24-hour coverage.
Domperidone enhances gastrointestinal motility by acting on dopamine D2 receptors in the GI tract, promoting faster gastric emptying and reducing bloating, nausea, and abdominal discomfort. The synergy between Esomeprazole and Domperidone makes ES-PROZOLE DSR a frontline therapy in acid reflux management and gastric motility disorders.
With WHO-GMP certified production standards, ES-PROZOLE DSR TAB meets the stringent quality, safety, and efficacy criteria demanded by global healthcare markets. It is formulated using advanced pelletization and delayed-release coating technology, ensuring bioequivalence, patient compliance, and consistent therapeutic outcomes.
✅ Indications / Therapeutic Uses
Gastroesophageal Reflux Disease (GERD)
Non-ulcer Dyspepsia
Acid Peptic Disorders
Chronic Gastritis
Functional Bloating and Nausea
Reflux Esophagitis
Delayed Gastric Emptying
Vomiting associated with gastric stasis
✅ Mechanism of Action
Esomeprazole irreversibly inhibits the H+/K+ ATPase enzyme system of gastric parietal cells, which is the final pathway for acid secretion, thereby reducing gastric acidity significantly and for a prolonged period.
Domperidone works by antagonizing dopamine D2 receptors in the GI tract and the chemoreceptor trigger zone, promoting gastric emptying and improving lower esophageal sphincter tone while minimizing symptoms like nausea and fullness.
✅ Dosage & Administration
Typical dosage: One tablet/capsule per day
Administration: Take orally on an empty stomach, preferably 30 minutes before breakfast
Duration: Course typically lasts 4 to 8 weeks, depending on indication
Always follow physician's guidance on duration and dosage
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