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Ceftriaxone Sodium & Sulbactam Sodium for Injection 187.5 mg is a high-potency combination antibiotic formulated for parenteral administration. This dry powder injection contains a fixed dose of Ceftriaxone Sodium, a broad-spectrum third-generation cephalosporin antibiotic, combined with Sulbactam Sodium, a potent beta-lactamase inhibitor. The inclusion of Sulbactam extends Ceftriaxone’s antibacterial activity to resistant strains that produce beta-lactamase enzymes, thereby improving treatment outcomes in bacterial infections. This injectable preparation is ideal for severe bacterial infections including respiratory tract infections, urinary tract infections, skin and soft tissue infections, and intra-abdominal infections. Its formulation as a sterile dry powder facilitates storage and convenient reconstitution prior to intravenous or intramuscular administration. This product is specifically developed for hospital and clinical settings requiring reliable and enhanced antibacterial therapy in adult and pediatric patients.
Key Features
| Features | Description |
|---|---|
| Formulation | Sterile dry powder for injection |
| Combined Dosage Strength | 187.5 mg per vial |
| Active Components | Ceftriaxone Sodium 150 mg + Sulbactam Sodium 37.5 mg |
| Antibacterial Spectrum | Effective against beta-lactamase producing bacteria |
| Route of Administration | Intravenous or Intramuscular injection |
| Packaging | Single-use sterile vial |
| Indications | Severe bacterial infections including respiratory and urinary tract infections |
| Stability | Stable dry powder requiring reconstitution before use |
| Attributes | Description |
|---|---|
| Drug Class | Third-generation cephalosporin with beta-lactamase inhibitor |
| Dosage Form | Dry powder for injection |
| Strength per Vial | 187.5 mg (Ceftriaxone 150 mg + Sulbactam 37.5 mg) |
| Mechanism of Action | Ceftriaxone inhibits bacterial cell wall synthesis; Sulbactam inhibits beta-lactamases |
| Reconstitution | Reconstitute with sterile water or appropriate diluent before administration |
| Storage Condition | Store in a cool, dry place below 25°C |
| Shelf Life | Typically 24 months from manufacturing date |
| Sterility | Aseptic manufacturing ensuring sterile product |
| Regulatory Compliance | Manufactured under GMP standards |
*Disclaimer: The above description has been AI-generated and has not been audited or verified for accuracy. It is recommended to verify product details independently before making any purchasing decisions.
The combination enhances the antibacterial spectrum by adding Sulbactam Sodium, a beta-lactamase inhibitor, which protects Ceftriaxone from degradation by beta-lactamase producing bacteria, leading to higher efficacy against resistant strains.
This preparation is designed for intramuscular or intravenous injection following reconstitution of the dry powder.
The dry powder injection should be stored in a cool, dry place below 25°C, protected from moisture, as per standard pharmaceutical storage guidelines.
While this product is generally suitable for clinical use including pediatrics, dosing must be determined by a healthcare professional based on patient age and weight.
It is indicated for the treatment of serious bacterial infections such as respiratory tract infections, urinary tract infections, skin and soft tissue infections, and intra-abdominal infections.
Ceftriaxone Sodium & Sulbactam Sodium for Injection 187.5 mg is a combination antibiotic that combines a third-generation cephalosporin with a beta-lactamase inhibitor. This combination is designed to enhance the efficacy of Ceftriaxone against a broader range of bacteria, especially those that produce beta-lactamase enzymes.
Key Features:
Form: Dry powder for injection.
Strength: 187.5 mg (combined dosage of Ceftriaxone Sodium and Sulbactam Sodium).
Ceftriaxone Sodium: Typically 150 mg (or as specified).
Sulbactam Sodium: Typically 37.5 mg (or as specified).
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