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Cefpirome Sulphate & Sulbactam for Injection 750 mg is an advanced combination antibiotic formulated as a dry powder for injection. It combines the potent fourth-generation cephalosporin, Cefpirome Sulphate, with Sulbactam Sodium, a beta-lactamase inhibitor that enhances antibacterial efficacy by inhibiting beta-lactamase enzymes produced by resistant bacteria. This injectable formulation, with a total dosage of 750 mg (typically 500 mg Cefpirome Sulphate and 250 mg Sulbactam Sodium), is designed to combat serious infections caused by multidrug-resistant Gram-positive and Gram-negative pathogens. It is widely used in hospital settings to treat complicated urinary tract infections, respiratory tract infections, intra-abdominal infections, skin and soft tissue infections, and septicemia. The dry powder format ensures stability and ease of reconstitution, enabling precise dosing and rapid administration. Its broad-spectrum activity with enhanced resistance to beta-lactamase degradation makes it an essential antibiotic for clinicians managing resistant bacterial infections in critically ill or immunocompromised patients.
Key Features
| Features | Description |
|---|---|
| Form | Dry powder for injection |
| Total Strength | 750 mg per vial (combined dosage) |
| Cefpirome Sulphate Amount | Typically 500 mg |
| Sulbactam Sodium Amount | Typically 250 mg |
| Antibiotic Class | Fourth-generation cephalosporin + beta-lactamase inhibitor |
| Spectrum | Broad-spectrum antibacterial effective against resistant Gram-positive and Gram-negative bacteria |
| Usage | Injection for treating complicated infections such as respiratory, urinary tract, intra-abdominal, skin, soft tissue infections, and septicemia |
| Stability | Stable dry powder requiring reconstitution before administration |
| Attributes | Description |
|---|---|
| Dosage Form | Injectable dry powder |
| Dosage Strength | 750 mg per vial |
| Composition | Cefpirome Sulphate 500 mg, Sulbactam Sodium 250 mg |
| Reconstitution | Requires reconstitution with appropriate sterile diluent before intravenous or intramuscular injection |
| Packaging | Sterile single-use vials |
| Storage Conditions | Store in a cool, dry place protected from light |
| Indications | Severe bacterial infections including urinary, respiratory, skin, intra-abdominal infections, and septicemia |
| Mode of Action | Cefpirome inhibits bacterial cell wall synthesis; Sulbactam inhibits beta-lactamase enzymes |
| Shelf Life | As per manufacturer specifications, typically 2 years |
| Administration Route | Intravenous or intramuscular injection after reconstitution |
*Disclaimer: The above description has been AI-generated and has not been audited or verified for accuracy. It is recommended to verify product details independently before making any purchasing decisions.
The injection typically contains 500 mg Cefpirome Sulphate and 250 mg Sulbactam Sodium, totaling 750 mg per vial.
Yes, after proper reconstitution with sterile diluent, the injection can be administered via both intravenous and intramuscular routes.
It is highly effective for treating complicated respiratory, urinary tract, intra-abdominal, skin and soft tissue infections, and bloodstream infections caused by resistant bacteria.
Sulbactam acts as a beta-lactamase inhibitor which prevents the enzymatic breakdown of Cefpirome by resistant bacteria, thereby extending its antibacterial spectrum.
The dry powder vials should be stored in a cool, dry place away from direct light to maintain stability.
Country Of Origin: India
Cefpirome Sulphate & Sulbactam for Injection 750 mg is a combination antibiotic that pairs a fourth-generation cephalosporin with a beta-lactamase inhibitor, making it effective against a wide range of resistant bacterial infections.
Key Features:
Form: Dry powder for injection.
Strength: 750 mg (combined dosage of Cefpirome Sulphate and Sulbactam Sodium).
Cefpirome Sulphate: Typically 500 mg.
Sulbactam Sodium: Typically 250 mg.
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