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BORTLIEVA (Bortezomib Injection IP 2 mg/Vial) is a targeted oncology injectable medication manufactured by Allieva Pharma Private Limited, specifically designed for the treatment of hematological malignancies such as multiple myeloma and mantle cell lymphoma. This scheduled drug is a reversible proteasome inhibitor that disrupts the 26S proteasome function, leading to the accumulation of misfolded proteins, inducing apoptosis in malignant plasma cells. BORTLIEVA is administered via intravenous or subcutaneous routes and is critical in both newly diagnosed and relapsed/refractory cases of multiple myeloma and relapsed mantle cell lymphoma. Each 2 mg vial is formulated for single-dose preparation to ensure dosage accuracy based on body surface area (1.3 mg/m² per dose). Given its potent mechanism and risk profile including peripheral neuropathy and thrombocytopenia, usage is strictly under physician supervision and requires prescription. Antiviral prophylaxis like acyclovir is recommended to mitigate herpes zoster reactivation risk during therapy. BORTLIEVA is made in India and available for bulk purchase from RADHAKRUSHNA MEDICALS with a minimum order quantity of 1 piece.
Key Features
| Features | Description |
|---|---|
| Active Ingredient | Bortezomib 2 mg per vial |
| Drug Form | Injection |
| Mechanism of Action | Reversible inhibition of 26S proteasome |
| Indications | Multiple Myeloma and Mantle Cell Lymphoma (relapsed/refractory) |
| Dosage | 1.3 mg/m² per dose on Days 1,4,8,11 of 21-day cycle |
| Route of Administration | Intravenous (IV) or Subcutaneous (SC) |
| Packaging | Single-dose vial, 2 mg each |
| Antiviral Prophylaxis | Recommended to prevent herpes zoster reactivation |
| Prescription Status | Prescription required, physician supervised |
| Manufacturer | Allieva Pharma Private Limited |
| Country of Origin | India |
| Attributes | Description |
|---|---|
| Brand Name | BORTLIEVA |
| Active Drug | Bortezomib |
| Concentration | 2 mg per vial |
| Formulation Type | Injection IP |
| Dosage Form | Injectable solution |
| Dosage Schedule | Days 1,4,8,11 of 21-day cycle |
| Administration Route | IV or SC |
| Therapeutic Area | Oncology - Hematological malignancies |
| Indications | Multiple Myeloma, Mantle Cell Lymphoma |
| Side Effects | Peripheral neuropathy, thrombocytopenia, nausea |
| Packaging Size | 1 vial per piece |
| Minimum Order Quantity (MOQ) | 1 piece |
| Prescribed By | Oncology specialists only |
| Storage Condition | Manufacturer instructions apply |
| Schedule | Scheduled drug |
| Manufacturer | Allieva Pharma Private Limited |
| Country of Origin | India |
*Disclaimer: The above description has been AI-generated and has not been audited or verified for accuracy. It is recommended to verify product details independently before making any purchasing decisions.
BORTLIEVA is typically administered at a dose of 1.3 mg/m² via IV or SC injection on Days 1, 4, 8, and 11 of a 21-day treatment cycle.
Yes, antiviral prophylaxis such as acyclovir is recommended to prevent herpes zoster reactivation during treatment.
Yes, BORTLIEVA is indicated for both newly diagnosed and relapsed/refractory multiple myeloma cases.
Common side effects include peripheral neuropathy, thrombocytopenia, nausea, diarrhea, constipation, and fatigue.
Yes, BORTLIEVA comes as a single-dose 2 mg vial suitable for precise dose preparation.
Country Of Origin: India
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