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BACLOSIGN 10 Tablet by Dr Precision is a potent centrally acting skeletal muscle relaxant containing 10 mg of Baclofen. Specifically formulated for managing muscle stiffness, spasms, and tightness in individuals suffering from neurological disorders such as multiple sclerosis, spinal cord injuries, cerebral palsy, and post-stroke conditions, BACLOSIGN 10 provides targeted relief by modulating neurotransmitter signals within the spinal cord. By selectively agonizing GABA-B receptors, it inhibits excitatory neurotransmitter release, thereby restoring muscle tone balance and improving range of motion. Manufactured under strict WHO-GMP conditions to ensure consistent quality and efficacy, BACLOSIGN 10 assures reliable therapeutic outcomes ideal for chronic neuromuscular disorder management. The oral tablet form ensures rapid gastrointestinal absorption and effective bioavailability, with a pharmacokinetic profile enabling sustained symptom control through multiple daily dosing. BACLOSIGN 10 is essential for enhancing patient mobility, reducing discomfort, and improving overall quality of life in long-term management of spasticity-related conditions.
Key Features
| Features | Description |
|---|---|
| Active Ingredient | Baclofen 10 mg |
| Therapeutic Class | Centrally Acting Skeletal Muscle Relaxant |
| Indications | Muscle stiffness, spasms, and tightness from neurological disorders (Multiple sclerosis, Spinal cord injury, Cerebral palsy, Stroke) |
| Mechanism of Action | Selective GABA-B receptor agonist reducing excitatory neurotransmitter release |
| Dosage Form | Oral tablet |
| Manufacturing Standards | WHO-GMP certified under Dr Precision label |
| Pharmacokinetics | Rapid GI absorption, 70-80% bioavailability, crosses blood-brain barrier |
| Excretion | Primarily renal |
| Half-life | 2 to 6 hours |
| Dosing Frequency | Two to three divided doses daily for sustained efficacy |
| Attributes | Description |
|---|---|
| Tablet Strength | 10 mg Baclofen |
| Tablet Type | Film-coated, oral |
| Packaging | Available in blister packs (manufacturer dependent) |
| Stability | Stable under normal storage conditions |
| Shelf Life | Typically 24 months (manufacturer specified) |
| Color | White to off-white |
| Size | Standard tablet size for easy swallowing |
| Usage | Prescription only |
| Storage Conditions | Store in a cool, dry place away from direct sunlight |
*Disclaimer: The above description has been AI-generated and has not been audited or verified for accuracy. It is recommended to verify product details independently before making any purchasing decisions.
BACLOSIGN 10 acts as a selective agonist of GABA-B receptors in the central nervous system, which inhibits excitatory neurotransmitter release such as glutamate and aspartate, reducing neuronal excitability and muscle spasticity.
Manufactured under WHO-GMP conditions with consistent quality, BACLOSIGN 10 has a well-established safety and efficacy profile, rapid absorption, and manageable pharmacokinetics supporting multiple daily dosing for chronic symptom control.
To maintain optimal plasma levels and minimize side effects, BACLOSIGN 10 is generally prescribed in two to three divided doses per day.
Yes, BACLOSIGN 10 is indicated for managing muscle stiffness and spasms associated with post-stroke spasticity, improving patient mobility and comfort.
BACLOSIGN 10 demonstrates rapid gastrointestinal absorption with peak plasma concentration within 2-3 hours, approximately 70-80% bioavailability, ability to cross the blood-brain barrier, and renal excretion, making it effective for central nervous system muscle relaxation.
Country Of Origin: India
BACLOSIGN 10 Tablet is a centrally acting skeletal muscle relaxant containing Baclofen 10 mg. It is used to relieve muscle stiffness, spasms, and tightness associated with neurological disorders like multiple sclerosis, spinal cord injuries, cerebral palsy, and stroke. BACLOSIGN 10 helps restore normal muscle tone and movement by modulating neurotransmitter signals in the spinal cord. Manufactured under strict WHO-GMP conditions, it offers reliable therapeutic efficacy and patient-friendly dosing for long-term use in chronic neuromuscular conditions.
This product is manufactured under the Dr Precision label, ensuring GMP-compliant quality and precision formulation standards.
BACLOSIGN 10 Tablet is a therapeutic formulation containing Baclofen 10 mg, a well-established centrally acting muscle relaxant widely prescribed for the management of spasticity due to neurological disorders. Baclofen belongs to the gamma-aminobutyric acid (GABA) analog class and functions by inhibiting the transmission of nerve signals in the spinal cord. It is particularly effective in reducing involuntary muscle stiffness, rigidity, and painful spasms that arise from upper motor neuron lesions. BACLOSIGN 10 is extensively used in chronic conditions such as multiple sclerosis, spinal cord injury or disease, cerebral palsy, and post-stroke muscle spasticity.
The mechanism of action of Baclofen involves selective agonism of GABA-B receptors in the central nervous system. By binding to these receptors, Baclofen inhibits the release of excitatory neurotransmitters like glutamate and aspartate, thereby reducing neuronal excitability. This action helps restore the balance between excitatory and inhibitory signals in the spinal cord and brain, resulting in decreased muscle tone, improved range of motion, and relief from spasticity. BACLOSIGN 10 plays a key role in improving motor function, enhancing patient mobility, and reducing discomfort in patients who experience chronic spasticity.
The pharmacokinetics of Baclofen support its use as an oral medication in tablet form. After administration, BACLOSIGN 10 is rapidly absorbed from the gastrointestinal tract, with peak plasma concentrations reached within two to three hours. The bioavailability of Baclofen is approximately 70 to 80 percent, and it readily crosses the blood-brain barrier to exert its therapeutic effect. It is primarily excreted through the kidneys, and its half-life ranges between two and six hours, making multiple daily doses necessary in most treatment regimens. BACLOSIGN 10 is usually prescribed in two or three divided doses per day to maintain optimal plasma levels and avoid peak-related side effects.
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Surat , India
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