ALUVA 200mg/50mg Tablet is a potent antiretroviral medication combining Lopinavir and Ritonavir for the effective treatment of HIV-1 infection in adults and pediatric patients. This fixed-dose combination functions by inhibiting the HIV protease enzyme to prevent viral replication, while Ritonavir boosts Lopinavir's plasma concentration through CYP3A metabolism inhibition. Administered as part of a comprehensive cART or HAART regimen, ALUVA helps reduce viral load, improve CD4 counts, and restore immune function. Formulated for twice-daily dosing with food, this tablet supports treatment adherence with its convenient fixed-dose composition. Packaged in bottles of 120 tablets, ALUVA requires storage below 30°C, away from light and moisture to maintain efficacy. It is prescribed under medical supervision with regular monitoring of liver and metabolic parameters to ensure safe long-term management of HIV infection.
Key Features
| Features | Description |
|---|---|
| Active Ingredients | Lopinavir 200mg and Ritonavir 50mg per tablet |
| Combination Type | Fixed-dose combination |
| Therapeutic Use | Treatment of HIV-1 infection |
| Mechanism of Action | Lopinavir inhibits HIV protease; Ritonavir enhances Lopinavir plasma levels by inhibiting CYP3A metabolism |
| Dosage | 2 tablets twice daily with food or as prescribed |
| Packaging | Bottle containing 120 tablets |
| Patient Population | Adults and pediatric patients under physician guidance |
| Storage Conditions | Store below 30°C, protect from light and moisture |
| Therapeutic Benefits | Suppresses viral load, increases CD4 counts, improves immune function |
| Usage Precautions | Administer only under strict medical supervision |
| Attributes | Description |
|---|---|
| Manufacturer | Abbott |
| Composition per Tablet | Lopinavir 200mg, Ritonavir 50mg |
| Formulation | Tablet |
| Indications | HIV-1 infection treatment |
| Recommended Dosage | Two tablets twice daily with food |
| Therapeutic Category | Antiretroviral / HIV Medicine |
| Storage | Below 30°C; protect from light and moisture |
| Packaging Details | Bottle of 120 tablets |
| Route of Administration | Oral |
| Regulatory Status | Prescription only |
| Drug Interactions | Contraindicated with certain drugs; physician consultation required |
| Monitoring Requirements | Liver enzymes, lipid profile, blood glucose |
| Therapeutic Regimen | Used as part of combination antiretroviral therapy (cART/HAART) |
*Disclaimer: The above description has been AI-generated and has not been audited or verified for accuracy. It is recommended to verify product details independently before making any purchasing decisions.
No, ALUVA 200mg/50mg should not be used as monotherapy. It must be administered as part of a combination antiretroviral therapy regimen under medical supervision to effectively manage HIV-1 infection.
ALUVA is contraindicated with certain medications due to potential interactions via CYP3A metabolism. A thorough review of the patient's current medications is essential before prescribing, and physician guidance is required to avoid adverse interactions.
Yes, ALUVA 200mg/50mg can be prescribed for pediatric patients infected with HIV-1, but only under a physician’s guidance and with appropriate dosage adjustments.
Regular monitoring of liver enzymes, lipid profile, and blood glucose is recommended during ALUVA therapy to manage potential side effects and ensure patient safety.
Ritonavir acts as a pharmacokinetic enhancer by inhibiting the CYP3A enzyme responsible for Lopinavir metabolism, thereby increasing and sustaining Lopinavir plasma levels for improved antiviral effect.
Country Of Origin: India
Product Name: ALUVA 200mg/50mg Tablet
Manufacturer: Abbott
Composition:
Therapeutic Category:
Antiretroviral / HIV Medicine
Product Description:
ALUVA 200mg/50mg Tablet is a fixed-dose combination of Lopinavir and Ritonavir, used in the treatment of Human Immunodeficiency Virus (HIV-1) infection. Lopinavir is a protease inhibitor that blocks viral replication, while Ritonavir boosts the effectiveness of Lopinavir by inhibiting its metabolism.
This dual-action therapy helps reduce viral load, increase CD4 cell counts, and improve immune function in HIV patients. ALUVA is generally used as part of a combination antiretroviral therapy (cART/HAART) regimen.
Indications:
• Treatment of HIV-1 infection in adults and pediatric patients (as per physician’s guidance).
Mechanism of Action:
Dosage & Administration:
Key Benefits:
Packaging: Bottle of 120 tablets (200mg/50mg).
Storage:
Important Notes:
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Rajkot , India
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