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1- Hydroxy benzotriazole anhydrous (HOBT)

Name: 1- Hydroxy benzotriazole anhydrous (HOBT)
SKU: 8494063
Price: 19.59 USD
Availability: InStock

Sold by avd pharmaceuticals private limited · Service Provider , Manufacturer, Distributor, Exporter, Startup · Pimpri-Chinchwad, Maharashtra, India

Price

₹ 19.59 /unit

In stock

MRP ~~₹ 24.49~~

Inclusive of all taxes

You Save: ₹ 4.90

Minimum order: 1 unit

Export Snapshot

MOQ

1 unit

Lead time

On request

Packaging

Standard export packaging

Shelf life / longevity

As per product specification

HSN Code

On request

Origin

India

Port of dispatch

On request

Export markets served

Global markets

Values shown are for avd pharmaceuticals private limited.

Suitable for

Importers · Distributors · Wholesalers

Pimpri-Chinchwad Dispatch on request Verified seller

avd pharmaceuticals private limited

Service Provider , Manufacturer, Distributor, Exporter, Startup · Pimpri-Chinchwad, Maharashtra, India

Manufacturer of Research Chemicals, Drug Substances, Drug Intermediates, Impurities, Specialty Chemicals, and Provider of Job Work & Toll Manufacturing Services for Pharmaceutical and Chemical Companies

Registered address: Pune, India. Industry: Chemicals, Dyes & Paints > Chemicals, Compounds & Formulations.

View profile All products

Established

2022

Employees

11–30

GST

27AAXCA5614Q1ZS

IEC code

Not shared

Export markets

Global markets

GlobalLinker Member Since

Jun 2025

Turnover

$250,000 - $1 MM

Incorporation Type

On request

Certifications & Awards

Product details

What are the specifications of this product?

Overview

1-Hydroxybenzotriazole anhydrous is a potent acylation catalyst and condensation agent used primarily in peptide bond formation. It prevents racemization and improves yields in carbodiimide-mediated coupling reactions. The anhydrous form is highly reactive and moisture-sensitive, often used in strictly anhydrous conditions for high-purity synthesis. It is valuable in the synthesis of pharmaceutical peptides, esters, and complex small molecules.

Product Description

1-Hydroxybenzotriazole Anhydrous (HOBT Anhydrous)

Description:
1-Hydroxybenzotriazole anhydrous is a potent acylation catalyst and condensation agent used primarily in peptide bond formation. It prevents racemization and improves yields in carbodiimide-mediated coupling reactions. The anhydrous form is highly reactive and moisture-sensitive, often used in strictly anhydrous conditions for high-purity synthesis. It is valuable in the synthesis of pharmaceutical peptides, esters, and complex small molecules.

Product Summary:

CAS Number: 2592-95-2
Molecular Formula: C6H5N3O
Molecular Weight: 135.12 g/mol
Synonyms: HOBt
Packaging: 25 kg fiber drum
Solubility: Soluble in polar organic solvents
Storage: Store in a dry, inert atmosphere
Toxicity: Explosive when dry; handle under controlled conditions

Applications:

Amide bond formation in peptide synthesis
Synthesis of esters and activated carboxylic derivatives
Pharmaceutical R&D

Description provided by avd pharmaceuticals private limited.

Specifications

Molecular Formula	C6H5N3O
CAS Number	2592-95-2
Physical State	Solid, crystalline powder
Purity	High purity, anhydrous grade
Storage Conditions	Store under inert gas in dry environment
Hazard Information	Explosive when dry; requires controlled handling
Recommended Usage	Use under strictly anhydrous conditions for optimal performance
Solubility	Soluble in polar organic solvents such as DMF, DMSO
Packaging Details	Available in 25 kg fiber drums to maintain integrity and safety

Use cases

Category	healthcare > apis > api intermediate
Primary application	Wholesale, distribution, and international sourcing
Brand	Not specified
Product type	Product

Logistics & handling

Lead time	On request
Packaging	As per buyer requirement
Storage condition	As recommended by supplier
Origin	India
Form	As listed by supplier

Commercials (this seller)

Minimum order	1 unit
Lead time	On request
Payment terms	As per negotiated commercial agreement.

Buyer questions

Frequently asked by buyers

Common questions B2B buyers ask before sourcing 1- Hydroxy benzotriazole anhydrous (HOBT). Answers compiled from verified sellers' commercial terms and platform data.

Q: How does the anhydrous form of 1-Hydroxybenzotriazole differ from its hydrated counterpart in peptide synthesis?

A: The anhydrous form of 1-Hydroxybenzotriazole is significantly more reactive and moisture-sensitive, making it suitable for strictly anhydrous peptide synthesis conditions where high-purity and improved coupling efficiency are required. Its use minimizes side reactions and racemization compared to hydrated forms.

Q: What safety precautions must be taken when handling 1-Hydroxybenzotriazole Anhydrous?

A: Because 1-Hydroxybenzotriazole Anhydrous is explosive when dry, it must be handled under controlled conditions with proper personal protective equipment, in a dry and inert atmosphere, avoiding friction, heat, or contamination with incompatible materials.

Q: Which solvents is 1-Hydroxybenzotriazole Anhydrous compatible with for optimal solubility?

A: It is highly soluble in polar organic solvents such as dimethylformamide (DMF) and dimethyl sulfoxide (DMSO), which are commonly used in peptide coupling reactions for better reagent performance.

Q: What packaging format is available for industrial and laboratory use of HOBt anhydrous?

A: HOBt Anhydrous is typically supplied in 25 kg fiber drums designed to maintain the chemical's anhydrous condition and ensure safe transportation and storage for industrial and professional lab environments.

Q: In which types of pharmaceutical synthesis is 1-Hydroxybenzotriazole Anhydrous most valuable?

A: It is most valuable in pharmaceutical peptide synthesis, ester synthesis, and the generation of activated carboxylic derivatives where racemization prevention and high coupling yields are crucial.

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